慢性肾脏病患者生活质量的初步分析.pdfVIP

·256· 竖脏病杂志2()()7年12月第7卷第6期 J Clin Nephrol December 20／)7，Vo1．7，No．6 慢性肾脏病患者生活质量的初步分析 高坤 孙伟 周栋 李国春 【摘要】 目的 应用改良的肾脏病生活质量量表1．3(KDQOL—SFTM1．3)对慢性肾脏病(CKD) 患者的生活质量进行初步分析。方法 采用问卷调查的方法收集44例门诊CKD患者的生活质量数 据进行分析。结果 18个维度中有11项a信度系数0．6，其中7项a信度系数超过了0．8。对反映 简化36医疗结局研究量表(SF-36)的8个维度采用因子分析法，经最大方差旋转后产生2个主成分， 共解释了64．66 的总方差。肾脏病相关生存质量(KDTA)总分与SF-36量表总分的相关系数为 0．421。不同性别在“总体健康”一项中差异有统计学意义(P=0．026)，肾功能正常与不全两组患者 在“症状与不适”方面的差异具有统计学意义。“症状与不适”、“睡眠”、“社会的支持”、“疼痛”4项均 与年龄呈负相关。结论 本改良量表基本适合我国国情，但需进一步改良与完善。 【关键词】 肾脏病，慢性；生存质量；信度；效度 Prelimma~ study of quality of life among the patients with chronic kidney disease GA0 Kun，SUN Wei，ZHOU Dong，et a1．Department of Nephrology，J iangsu Provincial Hospital of TCM， Nanjin 210029，China [Abstract] Objective To study the quality of life among the patients with chronic kidney dis— ease(CKD)through the modified KDQOL-SFT 1．3 short—form health survey．Method 44 patients with CKD were involved in this study．The data of KDQ0I，SFTM 1．3 short～forlTIS were collected and analyzed．Results The modified KDDQI—SFTM 1．3 showed internal consistency(every CronbachⅡ coefficients of 1 1 dimensions was greater than 0．6O)．Factor analysis resulted in tWO factors that were consistent with the theoretical hypothesis in some degree．They could be used tO explain 64．66 of the total variance．The correlation coefficient of the total score between the KDTA and the SF-36 was 0．421．There was significant difference in“General health”between male and female(P0．05)． There was also significant difference in“symptom／discomfort”between normal renal function griyo and renal failure group(P【)．05)．The scores of“symptom／discomfort“，“sleep”，“social support” and“pain”correlated with the age negatively(P()．05)．Conclusions The modified KD )LSFT 1．3 is suitable tO the condition of our country． [Key words] Chronic kidney disease；Quality of life；Reliability；Validity 肾脏病生活质量量表1．3(KDQOL-SFTM 1．3) 诊符合CKD诊断标准[3]的患者110例，均自