用于术前预测结直肠癌淋巴结转移的放射性诺模图的发展和验证(英文正文).pdf

V O L U M E 3 4 • N U M B E R 1 8 • J U N E 2 0 , 2 0 1 6 JOURNAL OF CLINICAL ONCOLOGY O R I G I N A L R E P O R T Development and Validation of a Radiomics Nomogram for Preoperative Prediction of Lymph Node Metastasis in Colorectal Cancer Yan-qi Huang, Chang-hong Liang, Lan He, Jie Tian, Cui-shan Liang, Xin Chen, Ze-lan Ma, and Zai-yi Liu Yan-qi Huang, Chang-hong Liang, Lan He, A B S T R A C T Cui-shan Liang, Ze-lan Ma, and Zai-yi Liu, Guangdong General Hospital, Guangdong Academy of Medical Sciences; Yan-qi Purpose Huang, Cui-shan Liang, and Ze-lan Ma, To develop and validate a radiomics nomogram for preoperative prediction of lymph node (LN) Southern Medical University; Lan He, metastasis in patients with colorectal cancer (CRC). School of Medicine, South China University of Technology; Xin Chen, Patients and Methods Affiliated Guangzhou First People’s The prediction model was developed in a primary cohort that consisted of 326 patients with Hospital, Guangzhou Medical University, clinicopathologically confirmed CRC, and data was gathered from January 2007 to April 2010. Guangzhou; and Jie Tian, Key Laboratory Radiomic features were extracted from portal venous–phase computed tomography (CT) of CRC. of Molecular Imaging, Chinese Academy Lasso regression model was used for data dimension reduction, feature selection, and radiomics of Sciences, Beijing, People’s Republic of China.