三联疗法联合布拉酵母菌根除成人消化系统幽门螺杆菌感染效果分析.docVIP

三联疗法联合布拉酵母菌根除成人消化系统幽门螺杆菌感染效果分析 　　DOI：10.16662/j.cnki.1674-0742.2017.11.152 [摘要] 目的 探?和分析三联疗法联合布拉酵母菌根除成人消化系统幽门螺杆菌感染的效果。方法 该研究方便选择该院在2015年5月―2016年10月期间收治的88例消化系统幽门螺杆菌感染患者作为研究主体，依据住院顺序均分为甲组和乙组，每组各44例患者，甲乙两组患者均通过三联疗法进行治疗，而甲组加用布拉酵母菌进行治疗，比较甲乙两组的幽门螺杆菌根除率、血清IL-8水平、血清IL-10水平以及不良反应发生率。结果 甲组患者幽门螺杆菌根除率（84.09%）高于乙组患者（63.64%），差异有统计学意义（χ2=4.768，P=0.029）。甲组患者的血清IL-8水平（84.69±9.27）ng/L少于乙组患者（105.64±10.42）ng/L，差异有统计学意义（t=9.964，P=0.000）。甲组患者的血清IL-10水平（66.85±7.21）ng/L少于乙组患者（87.59±9.32）ng/L，差异有统计学意义（t=11.675，P=0.000）。甲组患者不良反应发生率（11.36%）少于乙组患者（29.55%），差异有统计学意义（χ2=4.470，P=0.034）。结论 三联疗法联合布拉酵母菌根除成人消化系统幽门螺杆菌感染的效果确切，患者幽门螺杆菌的清除率较高，明显改善了患者的血清指标情况，并降低了不良反应发生的风险，值得推广 [关键词] 三联疗法；布拉酵母菌；成人消化系统；幽门螺杆菌；临床效果 [中图分类号] R573.1 [文献标识码] A [文章编号] 1674-0742（2017）04（b）-0152-03 Analysis of Infection Effect of Triple Therapy and Saccharomyces Boulardii Sachets in the Eradication of Helicobacter Pylori in the Adult Digestive System DAI Li-ming Digestive System Department， Jilin Public Security Frontier Corps Hospital， Changchun， Jilin Province， 130051 China [Abstract] Objective To discuss and analyze the infection effect of triple therapy and saccharomyces boulardii sachets in the eradication of helicobacter pylori in the adult digestive system. Methods 88 cases of patients with helicobacter pylori in the adult digestive system admitted and treated in our hospital from May 2015 to October 2016 were convenient selected and divided into two groups with 44 cases in each according to the admission order， both groups were treated with triple therapy， and the group A added the saccharomyces boulardii sachets for treatment， and the eradication rate of helicobacter pylori， serum IL-8 level， serum IL-10 level and incidence rate of adverse reactions were compared between the two groups. Results The eradication rate in the group A was higher than that in the group B（84.09% vs 63.64%）， and the difference was statistically significant（χ2=4.768， P=0.029）， and the serum IL-8 level in the group A was less than