中医药治疗骨质疏松症探究现状及进展.doc

中医药治疗骨质疏松症探究现状及进展 　　摘要：骨质疏松症全球发病率高，是诱发骨折的重要风险因素，严重影响患者生活质量。中医药在预防和治疗骨质疏松症方面有着独特的优势，开展了一系列临床及实验研究，取得重大进展。本文对近几年骨质疏松症的中医药治疗文献进行整理归纳，从单味中药、复方中药、其他治疗3个方面进行探讨，其中重点论述了近年来复方中药制剂在各种常见骨质疏松症治疗上的进展。以期读者从中得到启发，挖掘新思路，对进一步的研究抛砖引玉 关键词：骨质疏松症；中医药治疗进展；综述 中图分类号：R68文献标志码：A文章编号：1007-2349（2017）05-0090-03 [WT5HZ][JZ]Study on Status and Development of Traditional Chinese Medicine in the Treatment of Osteoporosis [WT5BZ][JZ]CHEN Zi-yi， ZHAO Zhong-wen [WT5”BX][JZ]（1.School of Postgraduate， Fujian University of Traditional Chinese Medicine， Fuzhou 350122， Fujian；[JZ]2.The Second Peoples Hospital of Fujian University of Traditional Chinese Medicine， Fuzhou 350001， Fujian） [WTHZ]【Abstract】[WTBZ]The high incidence of osteoporosis in the world is an important risk factor for fractures， which seriously affects the quality of life of patients. Traditional Chinese medicine in the prevention and treatment of osteoporosis has a unique advantage. A series of clinical and experimental research has been conducted， making a significant progress. The literatures of traditional Chinese medicine treatment of osteoporosis in recent years have been summarized and discussed from single Chinese medicine， compound Chinese medicine and other treatment in the paper， in which the progress of the traditional Chinese medicine in the treatment of various common osteoporosis are specifically discussed so as to give readers an inspiration and new ideas for further research. [WTHZ]【Key words】[WTBZ]osteoporosis， progress of traditional Chinese medicine treatment， summarization 骨?|疏松症（OP）是指低骨量和骨组织微细结构退化破坏的一种全身性骨骼疾病，骨的脆性增加从而容易发生骨折。骨质疏松症包括原发性和继发性两大类。原发性骨质疏松症又分为绝经后骨质疏松症（Ⅰ型）、老年性骨质疏松症（Ⅱ型）和特发性骨质疏松（包括青少年型）3种。继发性骨质疏松症指继发于其他疾病或者某种药物治疗导致的骨质疏松。骨质疏松症最典型的临床表现为疼痛、脊柱变形和发生脆性骨折。中医根据其临床症状体征，与“痹症”、“腰痛”相类似，将其归于“骨痿”、“骨枯”、“骨痹”范畴。近年来中医药治疗骨质疏松症取得很大进展，现综述如下 1单味中药药理分析 单味中药治疗骨质疏松症疗效确切，药理机制得到证实，近年来不断开展的药物研究为此提供了更为有力的证据。临床常用防治骨质疏松症的中药有补骨脂、淫羊藿、杜仲、骨碎补、菟丝子、续断、鹿茸、阿胶、黄芪、人参、枸杞、龟甲、葛根、牛膝、狗脊等。补骨脂作为临床治疗OP的常用药，近年研究层出不穷，药物有效成分被不断挖掘。邵航等[