内科药物治疗联合无创正压通气治疗COPD合并重症呼吸衰竭临床疗效观察.doc

内科药物治疗联合无创正压通气治疗COPD合并重症呼吸衰竭临床疗效观察 　　【摘要】 目的 研究慢性阻塞性肺疾病（COPD）合并重症呼吸衰竭老年患者采用无创正压通气（NIPPV）治疗的临床效果。方法 128例COPD合并重症呼吸衰竭老年患者， 按随机数字表法分为对照组和观察组， 各64例。对照组患者采用常规内科药物治疗， 观察组患者在对照组治疗基础上联合NIPPV治疗。观察两组患者治疗效果、血气情况、肺功能以及并发症发生情况。结果 观察组治疗总有效率为96.88%， 高于对照组的85.94%， 差异具有统计学意义（χ2=4.873， P0.05）。结论 NIPPV治疗COPD合并重症呼吸衰竭患者效果显著， 明显改善呼吸功能和肺功能， 不增加并发症发生率， 值得临床应用及推广 【关键词】 慢性阻塞性肺疾病；呼吸衰竭；无创正压通?猓涣菩? DOI：10.14163/j.cnki.11-5547/r.2016.33.012 Observation of clinical effect by internal medication combined with non-invasive positive pressure ventilation in the treatment of COPD complicated with severe respiratory failure WANG Xiao-dong. Department of Emergency， Liaoning Kazuo County Central Hospital， Chaoyang 122300， China 【Abstract】 Objective To research clinical effect by non-invasive positive pressure ventilation （NIPPV） in the treatment of senile patients of chronic obstructive pulmonary disease （COPD） complicated with severe respiratory failure. Methods A total of 128 senile patients of COPD complicated with severe respiratory failure were divided by random number table into control group and observation group， with 64 cases in each group. The control group received conventional internal medication for treatment， and the observation group also received NIPPV for combined treatment. Observation was made on curative effect， blood gas condition， pulmonary function and complications in both groups. Results The observation group had total effective rate as 96.88%， which was higher than 85.94% in the control group， and the difference had statistical significance （χ2=4.873， P0.05）. Conclusion NIPPV shows precise effect in treating COPD complicated with severe respiratory failure patients. This method can remarkably improve respiratory and pulmonary function， without increased incidence of complications. It is worth clinical application and promotion. 　　【Key words】 Chronic obstructive pulmonary disease； Respiratory failure； Non-invasive positive pressure ventilation； Curative effect 慢性阻塞