2006年湖南省流行性感冒病原学监测结果与分析.pdfVIP

1746 实用预防医学 2007年12月 第14卷 第6期 Practical Preventive Medicine，Dec．2007，Vol 14，No．6 文章编号：1006—3110(2007)06～1746—03 2006年湖南省流行性感冒病原学监测结果与分析 李芳彩 ，刘运芝 ，陈 长 ，张 红 ，黄 凰 ，陈柏塘 ，苏 良 ，石文松 ，谢 敏 ，王 媛 ，戴德芳 摘要： 目的 了解湖南省流感监测地区的流感流行状况及流感毒株的型别分布，分析其流行趋势，为流感防制提 供科学依据。 方法 采集流感样病例(IL1)的咽拭子标本，用传代狗肾细胞(MDCK)进行病毒分离，采用血凝抑制实 验(HI)进行流感病毒型别鉴定。分离的毒株再送国家流感中心(NIC)进行复核鉴定。 结 果 全省 12家哨点医院 3 499份ILl咽拭子标本，分离到毒株258株，分离阳性率为7．37％，经NIC最后复核鉴定的结果为：A(H1N1)亚型202 株，A(H3N2)亚型11株，B型43株，另有2株送NIC后转阴；流感及ILl暴发疫情病例咽拭子标本179份，分离到流感病 毒75株，分离阳性率为41，90％，分型鉴定为 A(H1N1)亚型 12株，B型62株，1株送国家流感中心后转阴。 结论 2006年湖南省流感监测地区全年均有流感活动，A(HIN1)亚型、A(H3N2)亚型和B型均能被分离到，A(H1N1)亚型为优 势株，而暴发疫情则以B型为主。 关键词： 流行性感冒(流感)；流感样病例(IL1)；病原学监测 中图分类号：R511．7 文献标识码：A Analysis on Influenza Pathogenic Monitoring in Hunan Province in 2006 LI Fang—cai，LIU Yan—zhi，CHEN Zhang，et a1．(Hunan Provincial Centerfor Disease Control and Prevention，Changsha 410005，Hunan) Abstract： Objective To understand the epidemic situation and the distribution of influenza virus types，and to analyze the epidemic trend for the disease contro1． Methods Throat swabs were collected from patients with influenza—like ill- nesses(JLI)．Influenza viruses were isolated by Madin—Darby Canine Kidney(MDCK)cell and identified by hemagglqtination inhibition(HI)test．The strains were then confirmed in the NationaI Influenza Center(NIC)． Results A totaI of 3，499 throat swab specimens were collected from 12 sentineI hospitals in Hunan in 2006，of which 258 strains were positive for influ— enza virus．The positive rate of isolation was 7．37％．After identifying by NIC，202 strains were influenza A — H1 N1，1 1 in- fluenza A — H3N2，43 influenza B virus，and 2 strains turned to negative．Altogether 179 throat swab specimens were collect- ed in the influenza outbreaks in 2006，of which 75 strains were positive for influenza virus．The positive