香蕉抗性淀粉对营养型肥胖大鼠减肥机理研究副本.pdf

现代食品科技 Modern Food Science and Technology 2014, Vol.30, No.8 香蕉抗性淀粉对营养型肥胖大鼠减肥机理的探究 唐健，夏雨，杜冰，张嘉怡，杨公明 （华南农业大学食品学院，广东广州 510642） 摘要：本研究利用从富含抗性淀粉的青香蕉而来的香蕉抗性淀粉干预营养型肥胖大鼠，观察其减肥功效，探索其减肥作用的机 理。结果表明：与肥胖对照组相比，香蕉抗性淀粉中、高剂量组能显著降低（P0.05 ）大鼠体重，分别降低7.26%和 7.99%；三个剂 量组都能在一定程度上改善大鼠血糖、血清瘦素、总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白等生化指标，提高大鼠粪脂率， 且呈剂量依赖关系，表明其具有较好的减肥功效。低、中、高香蕉抗性淀粉剂量组分别降低大鼠摄食量 16.63%、19.61%和 23.86%。 通过研究 3 种与控制食欲有关的胃肠激素，探索香蕉抗性淀粉的减肥机理。中、高剂量组能显著升高血清胆囊收缩素 CCK 水平 （P0.05 ），升高幅度达到 24.36%和 24.97%；低剂量组虽有升高，但没有显著性差异。低、中、高三个剂量组均能显著升高血清酪 酪肽PYY 水平（P0.01 ），升高幅度达到22.35%、28.34%和 34.84%；而对血清饥饿素ghrelin 无影响。可见香蕉抗性淀粉是通过刺激 影响食欲的胃肠激素分泌，控制大鼠摄食量、延长胃排空，达到减肥目的。 关键词：青香蕉；抗性淀粉；减肥机理；胃肠激素 文章篇号：1673-9078(2014)8-12-18 Mechanism of Weight Loss with Resistant Starch from Banana in Diet-induced Obese Rats TANG Jian, XIA Yu, DU Bing, ZHANG Jia-yi, YANG Gong-ming (College of Food Science, South China Agricultural University, Guangzhou 510642, China) Abstract: In this study, the anti-obesity effect of green bananas, rich in resistant starch, on diet-induced obese rats was evaluated and the mechanism of weight loss was studied. The results showed that, compared with rats in the obese control group, the body weight of rats in the medium- and high-dose (of banana resistant starch) groups reduced significantly (P 0.05) by 7.26% and 7.99%, respectively. Rats in all three groups showed improved biochemical profiles, including blood glucose, serum leptin, total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein levels, and a dose-dependent increase in fecal fat excretion, indicating that resistant starch from banana displayed good anti-obesity effect. Compared with the obese control