左磷右胺盐母液黏度测定与关联.pdfVIP

第 39 卷第1 期 化学工程 Vol. 39 No.l 2011 年 1 月 CHEMICAL ENGINEERING( CHINA) Jan. 2011 左磷右胶盐母液教度测定与关联 乔琳1 ，谭蔚1 ，崔波2 ，刘黎2 ，董远达2 ，刘丽艳1 (1.天津大学化工学院，天津 3仪泊72; 2. 东北制药总厂，辽宁洗阳 11∞26) 摘要:在液体泪合物教度理论的基础上，选取适宜的教度方程，通过对左磷右胶盐[(:t )2 顺 21 ， 22 环氧丙基磷酸 ( :t )苯乙胶]母液组分分析和蒙古度测定，关联得到了左磷右胶盐(左盐)母液和水、乙醇的教度理论计算公式，并将 所得蒙古度的计算结果和实验结果进行比较，结果表明:该毅度理论计算公式与含少量水的体系实验测定关联结果 较好，对含水量较多体系的实验测定结果存在-定的误差。事由度测定实验结果还表明，乙醇初一定量的水均能有 效降低母液秸度，为化学生产磷霉素俐的工程应用提供了一种简便途径。 关键词:母液; ( :t )2 顺21 ， 22 环氧丙基磷酸(士)苯乙胶;和度;磷霉素纳 中图分类号:0552.421;0645.161 文献标识码:A 文章编号:1∞15-9954 (2011 ) 01..{)(后6..Q4 Determination and correlation of mother liquor viscosity of R -( +)-α­ phenethylammonium. IR.2S-( - ) -cis-l ,2-epoxypropyl phosphonate l 1 2 2 2 1 QIAO Lin , TAN Wei , CUI B0 , LIU Ya0 , DONG Yuan-da , LIU Li-yan (1. School of Chemical Engineering and Technology , Tianjin University , Tia时in 3α)()72 ， China; 2. Dongbei Phannaceutical Factory , Shenyang 11∞26 ， Liaoning Province , China) Abstract: The mother liquor compone胞 and viscosity of R-( + )-α-phenethylammonium. IR. 25-( - ) -cis-l ,2- epoxypropyl phosphonate were analyzed on the basis of the liquid mixtures viscosity 出e。可. Wi由由e proper viscosity equations ，由e theoretical calculation formula of mother liquor viscosity of R-( + )-α-phenethylammonium. IR.25-( - ) -cis-l ,2-epoxypropyl phosphonate wi也 e出anol or w剖er was ohtained. 咀le calculated viscosity w幽 compared 明白白e experimental results. It shows that the theoretical viscosity calculation formula is well correlated wi由 the systems containing a litÙe water , but has some deviatio