医学英语-医英immune system.ppt

Lymphatic/Immune system Gang XIN Department of Microbiology and Immunology gxin@1979.10.26 immune system What is it? Where is it? How does it work? What is immunity? immunity Immune system Immune response Immunology Immunologist Immunodeficiency Immunocompromised IMMUNITY ←← IMMUNIS (EXEMPT) Latin: Protection from legal prosecution Now, in medical terms: free of disease. Bubble boy David Vetter(1971~1984) HIV and AIDS HIV - human immunodeficiency virus AIDS - acquired immune deficiency syndrome ARC: AIDS-related complex Opportunity Infection and Cancer Kaposi’s sarcoma Kaposi’s sarcoma lymphoma Functions of Immune system immune defence defense agaist infectious diseases immune surveillance kill cancer cells immune homeostasis ?maintain internal equilibrium? Where is immune system? Organs Cells Molecules Immune organs Central immune organs The site of generation, differentiation and maturation of lymphocytes including bone marrow thymus Bone marrow Thymus Peripheral immune organs and tissues The site where lymphocytes are resident and response to foreign antigens Lymph nodes Spleen MALT (mucosal-associated lymphoid tissue) SALT Lymph nodes Lymph nodes - Small bean-shaped glands Lymph - fluid within lymphatic vessels Lymphatic vessel - Lymphatic vessel - Lymph vessels that carry lymph to a lymph node are called the afferent lymph vessel, and one that carries it from a lymph node is called the efferent lymph vessel, from where the lymph may travel to another lymph node, may be returned to a vein, or may travel to a larger lymph duct. Collects excess tissue fluid throughout body Purifies it as it passes through system Returns it to circulatory system Lymph nodes Major groups of lymph nodes are located in the tonsils, armpits, neck, groin and mediastinum. John, 15/M tooth aches in left side of face one day later neck also started to hurt (only on the left side) after taking the penicillin for 2 days, tooth has for the