免耳瘢痕成熟过程中组织内氧分压的变化.pdfVIP

中国组织工程研究与临床康复 第 J2誊 第 42嬲 2008～10—14出版 JournalofClinicalRehabilitativeTissueEngineeringResearch October14,2008 Vo1．12,No．42 免耳瘢痕成熟过程中组织内氧分压的变化 谭 军，张 刚，李高峰 Changesinoxygenpartialpressureinrabbitearscar．tissuesduringthematureprocess TanJun，ZhangGang，LiGao-feng Abstract：Matureanimalmodelsofrabbitearscarsweremadefrom fcIrmationtomaturation．Tissueoxygenpartialpressurewas DepartmentofPlastic andCosmetic determinedby percutaneousoxygen monitoring at14，30，60and 90 days，and then pathology examination wasperformed． Surgery,Hunan Fourteendaysaftersurgery，brightredgranulationtissueshadalargenumberofinflammatory cellsandangiogenesis；oxygen ProvincialPeople’s partialpressurewas(0．81~0．25)kPa．Thirtydaysaftersurgery，thescarsweresignificantlyhigherthanthenormalskin，bright Hospital，Changsha red，madeupofalargenumberof fibroblastsandcapillaryintheorganizations；thepartialpressureofoxygenwas(1．98-+ 410005．Hunarl Province，China 026)kPa．At60daysaftersurgery．thescarswereshrinking；colorwaslight；theorganizationfibroblastcellsandmicrovessel decreased；partialpressureoxygen was (1．86~0．60)kPa．Ninetydaysaftersurgery，thescarswerefiat；colorwaswhite； TanJun．Chief organizationalstructurewasclosedtonormalskin；oxygenpartialpressurewas(13．70~1．16)kPa(PO．O1)．Duringthescar physlman， maturation process，thetissueoxygenpartialpressuredramatically increases．Improving the organizationoxygen mayhelp DepartmentofPlastic