阻塞性睡眠呼吸暂停综合征并发认知障碍的研究进展.PDFVIP

临床与病理杂志 2017, 37(6) 1316 J Clin Path ol R e s doi: 10.3978/j.issn.2095-6959.2017.06.041 View this article at: /10.3978/j.issn.2095-6959.2017.06.041 阻塞性睡眠呼吸暂停综合征并发认知障碍的研究进展 1 2 孔德强 综述 李战永 审校 (1. 廊坊市人民医院神经内科，河北 廊坊 065000；2. 廊坊师范学院生命科学学院，河北 廊坊 065000) [摘　要] 阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome ，OSAS)患者常伴有不同程度的认知 功能障碍，其认知功能下降的程度与 OSAS 的严重程度呈非线性关系。影响OSAS患者认知功能的 关键因素是睡眠片段和夜间低氧血症。持续气道内正压通气 (continuous positive air way pressure ， CPAP)是治疗 OSAS 的有效手段。 [关键词] 阻塞性睡眠呼吸暂停综合征；认知障碍；低氧血症；执行功能 Research progress on obstructive sleep apnea syndrome complicated by cognitive dysfunction 1 2 KONG Deqiang , LI Zhanyong (1. Department of Neurology, The People’s Hospital of Langfang City, Langfang Hebei 065000; 2. College of Life Science, Langfang Teachers University, Langfang Hebei 065000, China) Abstract Obstructive sleep apnea syndrome (OSAS) is often accompanied by varying degrees of cognitive dysfunction. The degree of patients’ cognitive decline was non-linear with the severity of OSAS. The key factors that affect the cognitive function of OSAS patients are sleep fragments and nocturnal hypoxemia. Continuous positive airway pressure (CPAP) is an effective means of treating OSAS. Keywords obstructive sleep apnea syndrome; cognitive dysfunction; hypoxemia; executive function 睡眠呼吸暂停综合征(sleep apnea syndrome ， 高碳酸血症。患者需在睡眠中反复唤醒，出现睡眠