近红外光谱法等三种方法测定安乃近片含量的比较 - 中国药事.pdf

2011 25 8 813 1 1 刘雁鸣, 蒋秋桃, 陈志能, 曾三平, 饶 泰 ( , 4 10001; ) : 比较 3种测定安乃近片含量的方法, 寻找 一种有利于药品监管部门快速进行安乃近片的检 及评价的方法分别采用近红外光谱法高效液相色谱法及容量分析法测定安乃近片中安乃近的 含量碘量法与HPLC 法近红外光谱法测定安乃近片含量有显著性差异近红外光谱法能对 不同企业生产的安乃近片作出准确快速无损的定量测定, 可用于药品的现场快速分析 : 近红外光谱法; 定量分析; 安乃近片 : R9272; R917 : A : ( 2011) Compare with the Methods of Nearinfrared Spectroscopy to Determine the Content of Analgin Tablets 1 Li Yanming, Jiang Qi tao, Chen Zhineng, Zeng Sanping and Rao Tai ( H nan Provincial Instit te for 1 Dr g Control, Changsha 410001; H nan Normal University) ABSTRACT: Objecti e Compare with the three methods to determine the content of Analgin T ablet to get the best method for dr g administration. Methods U se Nearinfrared Spectroscopy, H PLC and analytical chemistry method to determine the content of A nalgin T ablet. Results T here w ere marked difference in the there methods. Conclusion Nearinfrared Spectroscopy is a acc rate, rapid, nondamage and simple method to determine the content of Analgin Tablet. KEY WORDS: Nearinfrared Spectroscopy; assay ; Analgin Tablet , , , 3 1 [ 1] , MATRIXF ( : ; , , : OPU S 55, SFDA Ident Waters [ 2] [ 34] Alliance [ 56] [ 7] ( 2005 , , ) ( , WHO , : 100002200605, : 105 2h) , ( , B rdick JacksonTM ) ; , , ; 2009 2 , 21 2005 , 59 [ 8] 371 , 10 , , , : , , ; : ; T el: ( 0731) Email: 380852839@ qqcom 814