胶体金法检测幽门螺杆菌的临床价值 - 南华大学学报·社科版.pdf

58 Medical Science Journal of Central South China,January2013,Vol.41,No.1 文章编号:2095-1116(2013)01-0058-03 ·临床医学· 胶体金法检测幽门螺杆菌的临床价值 1 2 房晓芬 ,朱志超 (1. 山西医科大学第一医院消化科,山西太原030001;2.北京市通州区潞河医院消化科) 摘摇 要:摇 目的摇 探讨胶体金法检测幽门螺杆菌感染的临床价值。 摇 方法摇 门诊收集153例有上消化道症状 13 13 的成年患者,均行 C呼气试验、胶体金法和快速尿素酶试验3种方法检查幽门螺杆菌,以 C呼气试验结果为“金 标准冶,余两种检测方法分别与“金标准冶进行比较。 摇 结果摇 血清胶体金法可靠性较好,优于快速尿素酶法。 摇 结 论摇 胶体金法检测血清中幽门螺杆菌抗体,有较高的准确率及特异性,取材方便,操作简便,是较为理想的检测幽 门螺杆菌感染的方法。 13 关键词:摇 幽门螺杆菌;摇 胶体金法;摇 C呼气试验;摇 快速尿素酶试验 中图分类号:R573郾6摇 摇 摇 文献标识码:A The Clinical Value of Dot Immunogold Filtration Assay in Testing Helicobacter Pylori Infection FANG Xiaofen,ZHU Zhichao (Department of Gastroenterology,the FirstHosptial,ShanxiMedical University,Taiyuan,Shanxi030001,China) Abstract:摇 Objective摇 To investigatethe Dot Immunogold Filtration Assay (DI鄄GFA) in testing Helicobacter pylori (H.pylori) infection.摇 Method摇 153 outpatients with upper gastrointestinal symptoms were selected,who were detected 13 13 by C鄄Urea Breath Test and Dot Immunogold Filtration Assay and Rapid Urease Test.serologic testing. C鄄UBT was used asthe “goldstandard冶,andtheotherswerecomparedwiththe “goldstandard冶.摇 Results摇 DotImmunogoldFiltrationAs鄄 say was morereliableandsuperiorthanRapidUreaseTest.摇 Conclusion摇 DotImmunogoldFiltrationAssayhashigherac鄄 curacy and specificity in detecting helicobacter pylori antibody,with conveni