蟹源致病性拟态弧菌的粘附及侵袭特性adhesion and - 水产学报.pdf

28 5 Vol. 28, No . 5 2004 10 JOURNAL OF FISHERIES OF CHINA Oct. , 2004 : 1000- 0615( 2004) 05- 0541- 06 1, 2 1 1 胡守奎 , 李槿年 , 余为一 ( 1. , 2 00 6; 2. , 2 0061) : , ( ) , HX-4 , HEp-2 , HX-4 , HEp-2 , HX-4 HEp-2 , HEp-2 HEp-2 , 1h, , HEp-2 , : ; ; ; + : S945. 1 9 :A Adhesion and invasion of pathogenic Vibrio mimicus isolated from Eriocheir sinensis 1,2 1 1 HU Shou-kui , LI Jin-nian , YU We-i yi (1. College of Animal Husbandry and Fisheries, AnhuiAgricultural University, Hef ei 2 00 6, China; 2.Anhui Centerf or Disease Control and Prevention, Hef ei 2 0061, China) Abstract: It is well known that the most pathogenic bacteria can produce various virulence factors and they play function together and lead to the pathoenicity of bodis. The adhesion to cells or mucosa of pathogenic bacteria is the prime process which results in the infection of bodis. The adhesive factors of bacteria include pilus adhesion and non-pilus adhesion( such asflagella, outer membrane proteins and hemagglusion etc. ) . The adhesion to tissue- cells or mucosa of pathogenic bacteria mediating by pilus plays a key role in colonizing and propagating various virulence factors that result in the pathoenicity of bodis. In order to reveal the pathogensis mechanism of vibrio mimicus strain HX-4 in this study we used classic adhesive model-cell HEp-2 cells as cell model in vitro to test the adhesive ability of pathogentic vibrio mimicus HX-4 strain isolated from diseased riocheir sinensis to HEp-2 cells and the effect o