染病诊断技术国产化和产业化的必要性-许文波.ppt

* 基于症候群的实验室监测流程 5类症候群，包括： 呼吸道症候群 腹泻症候群 发热伴出疹症候群 发热伴出血症候群 脑炎脑膜炎症候群 确定临床症候群和标本采集原则与规范 选择哨点医院 病例信息采集 标本采集、运输和保存 标本检测 核酸检测 免疫学检测 病原分离 基因组信息 数据集成和信息分析 样本、毒种库管理 监测数据分析利用 其他分析 * 谢谢 * * So what is a Biohazard? NSF International defines biohazard as “an infectious agent, or part thereof, presenting a real or potential risk to the well-being of man, animals and/or plants, directly through infection or indirectly through disruption of the environment” * * 6 * 6 * * * * * * * * * 15 D5 endemic in Thailand D5 outbreak in Japan, started May 2006, no known epi-link. More than 270 cases in 2007, cases continue into 2008 (Jan-March) D5 cases (one or two cases) Denmark and Sweden April 2006 with epi-links to Thailand D5- Belarus Jan 2007 single case imported from Thailand D5 Vancouver April 2007, epi links to Japan. Japanese students assoc with case quarantined in hotel then sent back to Japan. D5 Switzerland since November 2006 with very close/identical sequences to the D5 virus endemic in Thailand and Japan.?No known epi-links associated with the Swiss D5 introduction.?The D5 Swiss virus was also linked to spread to Germany, Austria and Denmark. Case count Switzerland 2007; 1103. In 2008: 957 cases (March). D5 in Moscow Jan 07, epi-links to Thailand D5 New York virus epi-links to Japan (several episodes 2007) D5 New York July 07 epi links to Switzerland D5 Switzerland Jan 08. Epi-link and sequence identical to Berlin D5. Berlin D5 identical to the Swiss strain exported to south Germany early 2007. D5 San Diego Feb 08. Index case just returned from Switzerland. Eleven cases reported, all unimmunised. D5 Saint-Mandé, France, Feb 08 France (west) identical to Swiss virus, no epi-links, no details of outbreak. D5 Reims, France, Feb 08, no epi or molecular link to Swiss outbreak. ? 2008-04-11 - The Norwegian Institute of Public Health (NIPH) was notified on April 8 about 4 clinical cases of measles linked to an complementary medicines school in Norway. Three of the cas