医学免疫大题0809（Medical immunology 0809）.doc

医学免疫大题0809（Medical immunology 0809） 1 and hapten: a substance that has antigenicity only but does not have immunogenicity. It is called incomplete antigen, also called hapten. Hapten can be a complete antigen after binding with the vector. 2, fine adhesion molecules: is a large number of mediates cells or between cells and extracellular matrix contact and binding molecules collectively. According to their structural characteristics, they can be divided into integrin family, selectin family and so on. 3 Complement: a group of proteins that are not thermostable and activated by enzymes after activation on the surface of serum, tissue fluid, and cell membranes. 4 immunoglobulin: a globulin having antibodies or a chemical structure similar to antibodies. 5, cytokine: is a small molecule protein secreted by various cells of the body, and plays a biological role by combining the corresponding receptors on the surface of cells. 6, antibody affinity maturation: as antibody response continues, the antibody affinity produced by B cells continues to increase. Associated with high frequency mutations in somatic cells. 7, ADCC: antibody dependent cell-mediated cytotoxicity, which means that cells with lethal activity can directly kill target antigens through the Fc receptor expressed on their surface, and recognize the Fc segment of the antibody that binds to the target antigen. 8, PRR: pattern recognition receptor. Mainly refers to a class of receptors that are specific to the surface of innate immune cells, which can directly identify some specific molecular structures on the surface of pathogenic microorganisms or host apoptotic cells. Mainly includes MR, SR, TLR. 9 、 hypersensitivity reaction: when the organism is stimulated by certain antigens, the abnormal adaptive immune response is caused by the dysfunction of physiological function or the damage of tissue cells. 10. Central immune organ: the site where immune cells develop, differentiate, develop and mature, including b