仙人掌提取物抗溃疡作用（Anti ulcer effect of cactus extract）.doc

仙人掌提取物抗溃疡作用（Anti ulcer effect of cactus extract） Anti ulcer effect of cactus extract Update Date: 2010-08-12 Click: Cui Jingzhao, Chen Yuxing, Zhou Ruiling The cactus extracts to rats orally, stress, indomethacin, acetic acid, pyloric ligation gastric ulcer has obvious anti ulcer effect, and can significantly improve gastric prostaglandin E2 (PGE2) content. Keywords Guan Jian; cactus; extract; gastric ulcer; prostaglandin E2; Antiulcer Action of Extracts from Opuntia Dillenii on Rats Cui, Jingchao, Chen, Yuxing, Zhou, Ruiling Institute, of, Traditional, Chinese, Medicine, of, Guangdong Province, Guangzhou 510095 Abstract When administered orally to rats, the extrac ts from Opuntia dillenii was found to have action four experiment al Antiulcer in gastric ulcer models of, the stressrestration-model, indomethacin-model odel, and pyloric HACm, ligation-model.Statistical analysis showed that the difference between the control and treated groups was significant.In addition, the Opuntia dillenii was found to raise the content of PGE2 in the gastric juice in rats. Key, words, Opuntia, dillenii; Extract; Gastric, ULC, er; PGE2 The cactus Opuntia dillenii (Ker-gawl) Haw detoxification, nourishing the stomach, spleen, heart and stomach pain, for clinical treatment of gastric and duodenal ulcer, 1, 2, 3. Our experiments have proved that cactus has an obvious anti ulcer effect. In order to investigate the effective fraction of anti - ulcer effect of cactus, we studied the anti - ulcer effect of cactus petroleum ether, ethyl acetate and ethanol extract as follows: 1. 1 materials 1.1 animal: Wistar rats, weighing 200 ~ 250g, provided by the Guangdong Provincial Health Department of experimental animal, male with female. 1.2 drugs: cactus, petroleum ether, ethyl acetate, ethanol extract, by the chemical room of this institute, other chemical reagents are analytical pure. 2 methods and results 2.1 effect on stress gastric ulcer in rats: 56 male rats were divided into 7 groups accord