急性脑梗死早期血清TNF一仅和IL.6水平的变化及其意义.PDF

第39卷+第4期 浙江大学学报(医学版) Vol39No4 OFZHEJIANGUNIVERSITY(MEDICAL 2010丘 JOURNAL SCIENCES) 2010 http：／／www．journals．zju．edu．on／reed 急性脑梗死早期血清TNF一仅和IL．6水平的 变化及其意义 林久座1，缪克强2，张海霞3，孔庆钻1，袁日明1，王振威1，刘舜象1 (苍南县第二人民医院1．急诊科、2．内科、3．检验科，浙江苍南325802) [摘要] 化及其意义。方法：用酶联免疫吸附法，测定30例健康对照者和35例急性脑梗死(ACI)患者发病 6 方法检验相关性。结果：ACI患者血清TNF．Ot和IL-6均明显高于健康对照组，两者与发病6h内的 IL一6明显高于SCI患者，TNF一仅和IL一6对PCI风险评估有一定预测价值。 [关键词]脑梗死；急性病；肿瘤坏死因子仅；白细胞介素类；酶联免疫吸附测定；白介素6；进 展性脑梗死；价值 [中图分类号]R743．3 [文献标志码]A [文章编号] of serumTNF-OtandIL-6levelsinacutecerebralinfarction Changeearly andits significances LIN Jiu—ZUO，M1AOKe—qiang，ZHANGHai·xia，KONGQing—zuan，YUAN Zhen—wei，LIU Ri-ming，WANG Second Shun—xiang(DepartmentofEmergency，CangnanHospital，Cangnan325802，China) [Abstract] the of serumTNF—OtandIL石levelsinacute Objective：Toinvestigatechangeearly cerebralinfarctionandits TNF—dandIL-6levelsin30health significances．Methods：Serum subiects 6 and35 withacutecerebralinfarction(ACI)withinhoursofonsetweremeasured patients byenzyme linked deficits were immunosorbent allcases assay(ELISA)；neurologicalscores(NDS)indetermined， and usedfor serumlevelsof andIL-6inACI testwas correlation．Results：TheTNF—Q Spearman group were thanthoseinhealth andtherewasa correlationofTNF．dandIL-6 markedlyhigher subjects positive levelswith6h and withNDS an