当归、薄荷挥发油提取及包合工艺研究.PDF

摇摇708 环球中医药2017年7月第10卷第7期摇 Global Traditional Chinese Medicine,July2017,Vol郾10,No郾7 ·论著 · 当归、薄荷挥发油提取及包合工艺研究 张玲玲摇 倪健摇 杜雪莹摇 张欣摇 张娟摇 王海涛摇 杨春静摇 付京摇 张淼摇 郝晓凤摇 谢 立科摇 曲昌海 揖摘要铱摇 目的摇 优选当归、薄荷挥发油的提取及 茁鄄环糊精包合工艺。方法摇 采用水蒸气蒸馏 法进行提取,以加水倍量、蒸馏时间为考察因素,以挥发油体积为评价指标。 包合工艺以温度、搅拌 时间、挥发油与茁鄄环糊精和水的配比(mL 颐 g 颐 mL)为考察因素,以挥发油包合率和包合物产量为评 价指标,采用饱和水溶液法,以正交试验优选包合工艺。 采用X射线衍射法和显微镜法对包合物进 行验证。结果摇 优选的提取工艺为当归、薄荷加8倍量水,提取6小时;包合工艺为温度30益,搅拌 3小时,挥发油 颐 茁鄄CD 颐 水=1 颐 6 颐 60(mL 颐 g 颐 mL)。 验证结果显示包合物形成。 结论摇 所选工艺 合理、可行,可用于当归、薄荷中挥发油的提取及挥发油与茁鄄环糊精的包合。 揖关键词铱摇 当归;摇 薄荷;摇 挥发油;摇 提取工艺;摇 包合工艺;摇 茁鄄环糊精 揖中图分类号铱摇 R284.2摇 揖文献标识码铱摇 A摇 doi:10郾3969/ j郾issn郾1674鄄1749郾2017郾07郾007 Study on the extraction and inclusion process of volatile oil from angelicae sinensis radix and mentha canadensis摇 ZHANG Lingling,NI Jian,DU Xueying,et al. 摇 Institute of Chinese Pharmacy, Beijing University of Chinese Medicine,Beijing 100102,China Corresponding author:QUChanghai,E鄄mail:quchanghai@ 揖Abstract铱摇 Objective摇 To optimize the extraction process of essential oil from Angelica sinensis and Mentha Canadensis and the inclusion process of beta cyclodextrin. Methods摇 Steam distillation was used to extract,theamountofwateranddistillationtimeweretakenastheresearchfactors,andthevolume of volatileoilwasusedastheevaluationindex. Temperature,mixingtime,theratioofvolatileoil,betacy鄄 clodextrin andwater (mL 颐 g 颐 mL)were taken as the researchfactors of inclusion process. The inclusion rate and inclusion yieldof volatileoilwereusedasevaluationindexes,andsaturatedwater solutionmethod wasused,theinclusionprocesswasoptimizedby orthogonaltest. Theinclusioncomplexeswereverifiedby X ray diffraction and microscopy. Results摇 The optimized extraction conditions were 8 times amount of water,extracting for6 hours. Theoptimized inclusion conditionswerethetemperature is30益,stirringfor 3 hours,the volatile oi