可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床研究 潘凉泽1 .doc

可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床研究 潘凉泽1,谢延风1,石全红1,张超1,陆波1,明雪２（400016 重庆，重庆医科大学附属第一医院神经外科1；400016 重庆，重庆医科大学附属大学城医院妇产科2） 摘要: 目的 探讨可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床应用价值。方法 回顾性研究我院2011年9月至2014年11月窦镰旁大型脑膜瘤（肿瘤最大直径大于5cm）手术患者，根据瘤腔置入物不同分为可吸收人工脑膜组和明胶海绵组，比较两组术后瘤腔坍塌程度、术后出血、颅内压变化及住院时间长短。结果 可吸收人工脑膜组39例，瘤腔坍塌程度（21±6.2）%，术后出血2例，颅内压14.97±4.58 mmHg，住院时间11.12±1.54天；明胶海绵组39例，术后瘤腔坍塌程度（41±11）%，术后出血8例，颅内压16.97±6.62 mmHg，住院时间12.79±2.14天。两组比较有统计学意义(P 0. O5)。结论 可吸收人工脑膜能降低窦镰旁大型脑膜瘤术后出血的风险，有一定临床应用价值。 关键词: 可吸收人工脑膜；窦镰旁大型脑膜瘤；术后出血 Clinical research of absorbable artificial dura mater on preventing Postoperative hemorrhage in Large parasagittal and falcine meningiomas Pan Liangze1 Xie Yanfeng1 Shi Quanhong1 Zhang Chao1 Lu Bo1 Ming Xue2（1Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University,chongqing 400016,China；4Obstetrics and Gynaecology, University-Town Hospital of Chongqing Medical University, chongqing 400016,China) Abstract: Objective To observe the clinical effects of absorbable artificial dura mater on preventing postoperative hemorrhage in Large parasagittal and falcine meningiomas Methods A retrospective analysis from September 2011 to November 2014, the large parasagittal and falcine meningiomas (tumor diameter greater than 5 cm) surgery patients.According to the differences of tumor cavity implant ,the study is divided into absorbable artificial dura mater group and gelatin sponge group, Compare the degree of postoperative tumor cavity collapse, postoperative hemorrhage, intracranial pressure and the length of hospital stay between the two groups. Results Each group have 39 cases，the absorbable artificial dura mater group is superior to gelatin sponge group in the degree of postoperative tumor cavity collapse, postoperative hemorrhage, intracranial pressure and the length of hospital stay(P 0. O5). Conclusion The absorbable artificial dura mater can effectively reduce the risk of postoperative hemorrhage in Large parasagittal and falcine meningiomas.The stud