质子治疗肿瘤技术进展.pdf

质子治疗肿瘤技术进展 《TILS》——中国生命科学论坛 5 精华专刊 2004 年第 1 期 文章编号：06- （2004 ）063002005-3 中图分类号：R197 文献标识码：C 综述与专论 质子治疗肿瘤技术进展 Proton Therapy Technology Review 陈辉 （中国生命科学论坛技术产权项目交流与交易版 第1 版主） [责任编辑 TILS003] 摘要： 本文综述了国内外质子治疗肿瘤技术的研究现状，并指出了我国在应用质子治疗 肿瘤领域面临的很多问题。 关键词： 质子 肿瘤技术 进展 Brief introduction In 1946, someone tried to use proton beam produced by cyclotron to treat tumors. In 1950, Lawrence Berkely National Laboratory and H arvard Cyclotron Laboratory used proton beam to treat mammary cancer. Now, other tumor therapy instruments include X-ray therapy and r-ray therapy. Comparing to proton therapy, because proton has the special Bragg apex, the advantages are high power, strong penetrating and sh ort treating time. At one time, the proton therapy system has a long using time, so the treating cost is lower than X-ray therapy and r-ra y therapy, the venture of introducing into system is also low. The proton treating areas include prostate cancer, lung cancer, liver cancer and so on. And got the FDA cleared particle accelerator in Au gust, 2002. The key part of proton therapy system 质子治疗肿瘤技术进展 《TILS》——中国生命科学论坛 6 精华专刊 2004 年第 1 期 The key equipment of proton therapy system is ion source machine, inc lude two types, cyclotron and synchrotron. Cyclotron is first used in the field of tumor therapy. With the development of the treating exp eriments, synchrotron used in therapy is first produced by FNAL, it w as built in LLUMC. In 1990, Optivus Inc.(U.S) produced new synchrotro n based on the experience and patent of Loma Linda (the type name is Conforma3000