钬激光切除术+吡柔比星膀胱灌注治疗浅表性膀胱 - 第三军医大学学报.doc

论著 钬激光切除术治疗浅表性膀胱肿瘤疗效的临床研究 腾立新 辽宁 沈阳医学院奉天医院泌尿外科 摘要 目的 探讨经尿道钬激光切除术治疗浅表性膀胱肿瘤的疗效。方法 随机选取43例膀胱肿瘤患者作为观察组行经尿道钬激光切除术，另选取40例作为对照组行经尿道电切术，总结两组患者临床资料，并对手术时间、失血量、导尿管留置时间、肿瘤复发情况、肿瘤分期、膀胱穿孔例数等指标进行比较。结果：观察组获得准确肿瘤分期、分级与对照组无明显差异(P0.05)。术后肿瘤复发、尿道狭窄发生率均无明显差异(P0.05)。 手术时间较对照组长，差异有统计学意义(p0.01 )，但失血量、导尿管留置时间、住院时间均低于对照组，差异有显著统计学意义（p 0.01），同时 膀胱穿孔较对照组低，差异有统计学意义（p 0.05）。结论 钬激光切除术治疗膀胱肿瘤，方法简便、疗效可靠，具有创伤小、患者耐受性好、安全的优点，且在失血量、导尿管留置时间、住院时间方面比电切术更有优越性，值得临床推广应用。 关键词 钬激光切除； 膀胱肿瘤；疗效 The clinical study of Holmium laser resection of superficial bladder tumor efficacy Teng li xin Liaoning, Shenyang Medical College Mukden Urology Abstract Objective To investigate the clinical efficacy of transurethral holmium laser resection of bladder tumor． Methods Randomly selected 43 cases of bladder cancer patients as the observation group were randomly as signed to undergo ransurethral holmium laser resection of bladder tumor，and Forty casess a control group standard electrocautery transurethral resection bladder tumor．The mean operative time，indwelling urethral catheter time，mount of blood loss, postoperative recur rences，the case number of obtaining tumor stages，and bladder perforation were compared between the groups． Resultstumor stage or grade of the two group, has no significant difference (P 0.05). Tumor recurrence after surgery, the incidence rate of urethral stricture was no significant difference (P 0.05). Operative time than the control head, the difference was statistically significant (p 0.01), but Amount of blood loss, catheterization time, hospital stay were lower than the control group, the difference was statistically significant (p 0.01), while the bladder perforation than the control group, the difference was statistically significant (p 0.05). Conclusions：Holmium laser resection of bladder tumor, the method is simple, effective and reliable, with less trauma and well tolerated in patients, the advantages of safety, and in Amount of blood loss, catheterization time, hospital stay is more