Barrett食管269例内镜及活检病理分析.docVIP

Barrett食管269例内镜及活检病理分析[摘要] 目的：探讨Barrett食管的病理特征及电子胃镜特点。方法：对269例行电子胃镜检查并经病理检查证实的Barrett患者资料进行回顾性分析、总结。结果：Barrett患者以40~60岁居多，占66.2%（178/269），临床症状有不同程度重叠，主要表现为胃食管反流病（GERD）的症状，电子胃镜下表现为岛型176例，占65.4%；舌型66例，占24.5%；全周型27例，占10.4%。病理结果为肠化型上皮116例，占43.1%；胃底型上皮96例，占35.7%；贲门型上皮57例，占21.2%。结论：Barrett患者多见于中年人，临床上主要表现为GERD的症状，电子胃镜下以岛型多见，病理类型以肠化生最为常见。 [关键词] Barrett食管；电子胃镜；病理 [中图分类号] R571 [文献标识码] B [文章编号] 1673-7210（2011）12（b）-164-02 Analysis on endoscopic and biopsy of 269 cases of Barrett’s esophagus HUANG Da1, LIANG Mingpei2 1.Department of Gastroenterology, the People’s Hospital of Jingxi Town, Guangxi Zhuang Autonomous Region, Jingxi 533800, China; 2.Department of Editorial Office, Youjiang Medical Jourrnal Affiliated Hospital of Youjiang Medical College for Nationalities, Guangxi Zhuang Autonomous Region, Baise 533000, China [Abstract] Objective: To explore the pathological and electronic gastroscope property in patients with Barrett’s esophagus. Methods: Total of 269 patients with Barrett’s esophagus which diagnosed through routine electronic gastroscopy and pathology were enrolled in this retrospective analysis. Results: Majority of patients were between 40-60 years old. There were some degrees of overlap for clinical symptom among these patients which mainly expressed as the symptom of GERD. Under electronic gastroscopy, appearance of Mashima type was investigated in 176 patients (65.4%), tongue type change was found in 66 patients (24.5%), and the remaining were whole-week type change (10.4%). The results of pathological changes showed that the normal squamous epithelium was replaced by intestinal epithelium (43.1%), gastric epithelium (35.7%), and borderline epithelium (21.2%) separately. Conclusion: Barrett’s esophagus is mainly seen in middle age population. Majority of symptoms for these patients are expressed as GERD. Mozhima type’s appearance is the main finding in gastroscopy and intestinal metaplasia is the main change in pathology. [Key words] Barr