六种静脉输液品种渗透压摩尔浓度考察结果分析-中国药品标准杂志.PDF

Drug Standards ofChina 2010, Vol11No5 2010 11 5 351 王波, 李斌, 孙吉令 (, 250101) : 探讨静脉输液渗透压摩尔浓度存在的问题: 通过对6种静脉输液品种的渗透压摩尔浓度进 考察, 对发现 的问题进 分析: 大多数考察样品渗透压摩尔浓度测定结果偏低渗; 不同生产企业的同一品种, 渗透压摩尔浓度测定 结果相差大; 同一生产企业不同批次的同一品种, 渗透压摩尔浓度测定结果也存在差异: 为确保临床用药安全有效, 企业应重视对静脉输液渗透压摩尔浓度的控制,并在质量标准中制订合理的渗透压摩尔浓度限度 : 静脉输液; 渗透压摩尔浓度 : 917 : A : 1009- 3656( 2010) - 5- 351- 4 Analysis about Results on Osm olality of Six Species Intravenous Transfusions W ang Bo, LiBin, Sun Jiling (Shandong P rov incia l Institutef or Drug Control, J inan 250101) Abstract Objective: D iscuss problem about osmolality of intravenous transfusions. M ethods: Through consideration to osmolality of six species Intravenous transfusions, analyze discoverable problemsR esults: Osmolality ofmajority samples are leaning hypoosmotic; same species of different produce business, their osmolality have large difference; different batch samples of same species, same pro duce business, their osmolality also have differenceConclusions: To ensure the safety and utility of clinicalmedication, pharmaceuti calbusiness should reconsolidate the control to osmolality of intravenous transfusions, and formulate reasonable osmolality lmi it in drug quality specification K ey W ords: Intravenous transfusions; Osmolality () - 1 298mOsmol kg (), 280~ 310 STY1 mOsmol kg- 1[ 1] , , ; ( , ) , , ; ; , ; ; [2] , ; ; ! 2000 , , 2 (), 2 方法 [34] - 1 , , , 200 mOsmol kg