lecture-1课件.ppt

Biochemistry;授课老师：洪梅 生命科学学院 email: mh2788@scau.edu.cn 授课安排：1-14周，周二7、8节 周四3、4节 教材：生物化学教程 王镜岩 朱圣庚 徐长法编著 高等教育出版社 参考书籍： 简明生物化学 主编 王炜 副主编 王灿华 科学技术出版社 Lehninger Principles of Biochemistry DL Nelson, MM Cox W. H. Freeman and company; 6th edition (2013);考试和评分：本课程将会有两个考试，期中考试将在第八周。期末考试时间根据教务处安排。主要考试内容将会是9-16周的内容，但也会有部分期中考试前的内容，占大约30%。 评分：平时成绩: 35% (包括考勤、课堂作业、课堂报告） 期中考试(开卷、英语题目）：25％ 期末考试：40％;Presentation;What is biochemistry?;Categorization of Biochemistry;Why do we need to study biochemistry?;What do we study in biochemistry?;History of modern biochemistry;History of modern biochemistry (cont.);Biochemistry and molecular biology are both biological sciences that study living organisms in cellular and molecular levels. The former one is more focused on the chemical process within living organisms while the latter emphasizes more on the structure and function of biological molecules, especially nuclei acids.;An overview of biochemistry;Carbohydrates:;Carbohydrate functions:;Lipids:;Lipid functions:;Proteins:;Protein functions:;3D protein structure;Nucleic acids:;Nucleic acid functions:;Interactions between macromolecules:;轮剂戎鱼后垮翻葬壮态颈标怎懊窑戳泄今仍匪桓魄鞭沼家责坷导挠零埔训lecture-1课件lecture-1课件;Contents of the course;The applications of biochemistry;Gene therapy-insertion of genes into an individuals cells and tissues to treat a disease.;;Understand the underlying mechanisms of diseases, target drugs to the right place;Summary:;Molecules and their interactions in the cell;Chemical elements in living organisms: ;Covalent bonds energy- electron-pair sharing;The bonds in living organisms;Non-covalent bonds: flexible, need low energy to break the bonds, weak chemical forces: Hydrogen bonds （氢键, 12-30kJ/mol ）: the attractive interaction of a H atom (the electron receptor) with an electronegative atom such as N, O or F (the electron donor). ;Hydrogen bonds in water (intermolec