46例儿童咳嗽变异性哮喘的呼吸阻抗肺功能测定及过敏原检测分析.pdfVIP

· 940· 中国妇幼保健2008年第23卷 46例儿童咳嗽变异性哮喘的呼吸阻抗肺功能测定及过敏原检测分析 陈宏君 谭娴玲 邹商群 周玲飞 丘丽红 广东省珠海市妇幼保健院儿二科 519000 中国图书分类号 R725．6 文献标识码 B 文章编号 1001-4411(2008)07．0940-03 【摘 要】 目的：探讨儿童咳嗽变异性哮喘 (cVA)的肺功能特征及过敏原检测结果的特征。方法：选择46例儿童CVA 患者作为研究组，同时选取同期就诊的急性支气管炎患儿25例作为对照组，两组患儿同时进行了呼吸阻抗肺功能检测及过敏原 皮肤点刺检测，另外对于气道阻力增高者加做支气管舒张试验。结果：CVA患儿均存在气道阻力不同程度的增高，其阻力增高 程度与对照组相比有显著差异，气道阻力增高者舒张试验阳性率为75％，CVA组过敏原检测的阳性率与急性支气管炎组相比较 有显著差异。结论：CVA患儿大部分有可逆性气道阻塞，并且其发病与过敏因素关系密切，因此对长期慢性咳嗽患儿进行肺功 能检测及过敏原检测有助于明确病因诊断。 【关键词】 咳嗽变异性哮喘 呼吸阻抗 过敏原检测 儿童 Measurement of respiratory impedance＆pulmonary functions and analysis of aller- gen on 46 children patients with cough variant asthma CHEN Hong—Jun．TAN Xian— ng，ZOU Shang—Qun et a1．Department ofPediatrics H，Zhuhai Maternal and Chil— dren Healthcare Hospital of Guangdong Province，Zhuhai 5l9Oo0，China (Abstract) Objective：To discuss and assess the characteristics of pulmonary functions and the characteristics of test result of aller- gen in children patients with cough variant asthma(CVA)．Methods：Sel~ted 46 children Cases with CVA as the study group and 25 chil· dren cases with acute bronchitis as the control group．The two groups of children were ven the pulmonary function test for respiratory imped· ante and the skin prick test for analysis of allergen．Bronchial dilatation test Was also performed O11 patients with airway resistance increase．Results：The test showed that the airway resistance of CVA patients had increased at different levels，and there Was an obvious difference compared with the cases from the control group．The positive pementage of patients who had airway resistance increase Was 75％ shown in the bronchial dilatation test．The positive percentage in the allergen test Was greatly different from the control group．Conclusion： Most CVA children patients may have the reversible airway obstruction which is greatly in relation to the allergic factors．Therefore，it will he