基于激发荧光断层成像的多肿瘤重建-浙江师范大学.PDF

373 () Vol.37,No.3 20148 Journal of Zhejiang Normal University(Nat.Sci.) Aug.2014 :1001-5051(2014)03-0288-06 1 1 1,2 2 3 3 , , , , , (1., 321004;2. , 710071;3., 100044) :,,FMT/micro-CT ,CT ., ,. :;;; :TP391 :A Reconstruction of multiple tumors based on the fluorescence molecular tomography 1 1 1,2 2 3 3 NI Yingjie , ZHAO Jianmin , ZHU Xinzhong , ZHANG Qian , AN Yu , XU Han (College of Mathematics ,Physics and Inf ormation Engineering ,Zhejiang Normal University ,Jinhua Zhejiang 321004,China;2.School of Life Sciences and Technology ,Xidian University ,Xi′an Shanxi 710071,China;3.School of Computer and Information Technology ,Beijing Jiaotong Univeisity ,Beijing 100044,China) Abstract:For diagnosing and reconstructing multiple lesions accurately,a double tumors mouse model and FMT/micro-CT imaging system were built,fluorescence images and CT data of mouse were obtained by using FMT/micro-CT imaging system.The iteratively shrinkage method was chosen to reconstruct the double tumors mouse model.The result showed that the double tumors was reconstructed successfully.The result suggested that FMT would be available for multiple tumors in vivo. Key words:fluorescence molecular tomography;multiple tumors;reconstruction;iteratively shrinkage 0 [1] . ,., ,, [2-3] , ., :2013-12-26;:2014-02-20 :61272468) :(1989 -),,,.:. 3 ,: 289 ,、、、、,, [4-6] , . ,. ,,, ., .,,. ,,FMT/micro-CT , CT ,. ,,