丹参对应激大鼠血液流变性的影响.PDFVIP

·34 · J . of Chinese Microcirculation Feb. 2003 ,Vol. 7 ,No ,1 ( ) 文章编号 : 1007 - 8568 2003 01 - 0034 - 02 ·实验研究 · 丹参对应激大鼠血液流变性的影响 胡旺平 , 李雪梅 , 化长林 , 李立中 【摘要】 目的 探讨丹参对应激大鼠血液流变性的影响。方法 采用血液粘度计检测血液流变学 指标 ,荧光法检测血浆去甲肾上腺素的含量。结果 束缚应激大鼠血浆去甲肾上腺素的含量增高 ,全血比 粘度、血浆比粘度、红细胞变形指数、聚集指数、压积、血浆纤维蛋白原含量等均增高。经相关分析,去甲肾 上腺素含量与血液流变学各指标呈中高度相关。胃灌丹参后 ,上述各指标均显著下降。结论 丹参能明显 改善应激大鼠的血液流变性 ,可能是通过减少去甲肾上腺素的含量。 【关键词】丹参 ; 应激 ; 大鼠 ; 血液流变学 ; 去甲肾上腺素 中图分类号: R331 文献标识码 : B Effect of Radix Salviae Miltiorrhiza on the Hemorrheological Characteristics in Stressful Rats HU Wan - in , LI Xue-mei , HUA Chan -lin , et al. De artment o Ph siolo , Xiannin Medical g p g g p f y gy g Colle e , Xiannin 437100 , China g g 【Abstract 】 Ob ective To study the effect of radix salviae miltiorrhiza on the hemorrheolo gy in rat j stress. Methods The content of lasma noradrenaline and hemorrheolo ical characteristics were observed. p g Results When the content of noradrenaline was increased , whole blood viscosity , plasma viscosity , the idex of er throc tic a re ation and deformation , hematocrit , and lasma fibrino en were increased in stressful rats. Treated y y gg g p g b radix salviae miltiorrhiza , the above arameters were si nificantl decreased. Conclusions Radix salviae miltior y p g y rhiza can obviousl im rove the hemorrheolo ical characteristics of stress rat b reducin noradrenaline content in or y p g