localspreading炎症局部蔓延.ppt

Locus: mucous membrane, serosa, loose connective tissue, skin Manifestation: inflammatory edema, blister, cavity effusion, serous catarrh Sequel: absorption Definition : The inflammation exudate contains plentiful fibrinogen, then forms fibrin . Cause: severe vascular injury—bacterial toxin，Hg, urea Locus: mucous membrane, serosa, lung Manifestation: Pseudo-membranous inflammation--dysentery, diphtheria rheumatic pericarditis---Hairy heart（绒毛心） lobar pneumonia Superficial Suppuration Location: mucosal or serosa surface Features: Pus formation, Suppurative Catarrh Empyema a collection of pus in a hollow viscus, e. g. in the gall-bladder or fallopian tube, serous cavity Definition: wide-spread purulent inflammation in loose tissue Locus: skin, muscle and appendix Causes: hemolytic streptococci 溶血性链球菌：透明质酸酶，链激酶 Inflammation associated with conspicuous haemorrhage as a result of vascular damage. 菌血症 Bacteremia: organisms→ blood 毒血症 Toxemia: toxin→ blood 败血症 Septicemia: ①+② 脓毒败血症 Pyaemia: pyogenic organisms Causes of chronic inflammation supervening on acute 继发于急性炎症之后 due to repeated bouts of an acute 急性炎症反复发作 at beginning: Chronic granulomatous inflammation慢性肉芽肿性炎 causes of granulomas Features: foreign bodies Foreign body giant cells: seen in association with particulate insoluble material. Nuclei scattered throughout cytoplasm. 1.颈部淋巴结炎 2.淋巴结结核 3.转移癌 4.恶性淋巴瘤 5.甲状腺疾病 损伤与抗损伤斗争结果既为炎症的结局: 抗损伤损伤→炎症痊愈（大多数） 损伤抗损伤→炎症蔓延扩散（极少数） 抗损伤=损伤→炎症迁延不愈，转为慢性（少数） 痊愈 Healing 迁延为慢性 Delay and Persistence 蔓延扩散 Spreading 局部蔓延 local 淋巴道蔓延 Lymphatic 血道蔓延 Blood vessels outcome of acute Inflammation Return to normal vascular permeability Removal of fluid and protein Macrophage pinocytosis Phagocytosis by neutrophils Necrotic debris by macrophages Eventual exodus by macrophages Events in the complete resolution of inflammation 皮肤或粘膜深在的组织坏死脱落后所留下的组织缺损 Local spreadin