modulationofsox10hif-1αsurvivinandyapbyminocyclinein.ppt

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modulationofsox10hif-1αsurvivinandyapbyminocyclinein.ppt

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Modulation of Sox10, HIF-1α, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult? Qi Li, Masayuki Tsuneki, Michael Krauthammer, Rachael Couture, Michael Schwartz, Joseph A. Madri? The American Journal of Pathology? Volume 185, Issue 9, Pages 2364-2378 (September 2015) DOI: 10.1016/j.ajpath.2015.05.016 Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?1 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?2 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?3 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?4 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?5 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?6 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Figure?7 The American Journal of Pathology?2015 185, 2364-2378DOI: (10.1016/j.ajpath.2015.05.016) Copyright ? 2015 American Society for Investigative Pathology Terms and Conditions Minocycline treatment elicits proliferation and reduces caspase 3 activation of reduced oxygen-cultured secondary neurosphere neural stem cell (NSC) cultures and increases in Sox10, HIF-1α, PCNA, and cleaved notch1 expression in reduced oxygen-cultured (HX) C57BL/6 NSC compare