功能影像学技术在头颈部肿瘤放疗计划制定、疗效评估和个体化治疗中的应用幻灯片.pptx

Functional Imaging for Radiation Treatment Planning, Response Assessment, and Adaptive Therapy in Head and Neck Cancer;Role of routine and functional Imaging (FI);Benefit of FI;About this article;Part I Role of Functional Imaging in Radiation Therapy Planning;PET-based Tumor Target Contouring;Example of automated delineation;Status of PET-contouring at present;PET-based Radiation Therapy Planning;PET-based Radiation Therapy Planning;;Adaptive Radiation Therapy Planning;Adaptive Radiation Therapy Planning;Adaptive Radiation Therapy Planning;;Adaptive Radiation Therapy Planning;Mainly issues of FI to guide A-RT planning;PART II Functional Imaging for Disease Response Assessment;Functional MR Imaging Techniques;Dynamic Contrast-enhanced Imaging;Previous studies of DCE MRI;(a) Axial T1-weighted MR image obtained for planning of chemoradiation therapy in a 62-year-old man shows a primary SCC in the left aspect of the tongue base (T4N2bM0) (arrow) and a nodal metastasis (arrowhead). (b, c) Axial dynamic contrast-enhanced MR images before and after RT show increased vascular permeability (Ktrans) before radiation therapy in the primary tumor (arrow in b) and cervical node (arrowhead in b) decreased permeability after 11 fractionated doses of radiation therapy in the tumor (arrow in c) and node (arrowhead in c). These findings are indicative of therapeutic response.;Diffusion-weighted Imaging;;;Other fMRI techniques;Conclusions