反流性食管炎的临床分析..doc

反流性食管炎的临床分析 王 凡，刘 宾，邸 霞，樊宇靖，李 莉 王凡，刘宾，邸霞，首都医科大学附属北京同仁医院消化内科 北京 100730 樊宇靖，李莉，首都医科大学研究生院 北京 100069 王凡，女，1975－06－26生，北京市人，汉族。1999年首都医科大学临床医学学士，在读硕士，主治医师。主要从事反流性食管炎疾病的研究。 通讯作者：王凡，100037，北京市海淀区甘家口商场中纺宿舍804.vitaminfan@ 电话　　 【摘要】　目的　通过对我院24年间胃镜检查后诊断的反流性食管炎（RE）病例的回顾性总结分析,探讨反流性食管炎的内镜和临床特点。方法　1982年1月至2006年2月在我院就诊并行胃镜检查诊断为反流性食管炎4311例,按洛杉矶标准进行分级,分析患者年龄、性别、症状、伴发疾病及与各项检查的关系。结果 RE占总胃镜检查人数的8.39% , 1996年至2005年间达12.3％。男女之比为1.97:1。RE平均年龄(50.98±15.18)岁,52.2%RE≥50 岁。RE患者中22.1％合并消化性溃疡。仅4.0%有典型的反流症状。RE 以轻度为(洛杉矶标准的A、B 级) 多见,占74.70% ,中、重度较少（25.3％）。结论　我院RE的胃镜检出率较高8.39％，为目前门诊病人的常见病，多发病；患病者以男性老年人多见,以轻度RE为主；合并消化性溃疡可能是发生RE的危险因素；仅依据反流症状来诊断RE的敏感性较低,内镜对RE 的诊断具有重要意义。 【关键词】　反流性食管炎；内窥镜检查； Clinical analysis of reflux esophagitis 　Fan Wang, Bin Liu, Xia Di, Yu-jing Fan, Li Li Fan Wang, Bin Liu, Xia Di, Department of Gastroenterology, Beijing Tongren Hospital, Beijing 100730,China Correspondence to:Dr.Fan Wang 【Abstract】　Objective To investigate clinical and endoscopic characteristics of reflux esophagitis (RE) in Chinese population according to the retrospective analysis of RE in the past 24 years. Methods 4311cases of RE were diagnosised in our department by endoscopy according to the Los Angeles grading system, age, sex, symptom, accompanied diseases and each examinations were analyzed. Results 　RE accounted for 8.39% of the total endoscopy number , the present of RE during 1996-2005y was significantly elevated to 12.3%.Male vs female was 1.97:1. Mean age was(50.98 ±15.18) years old .52.2% of RE patient were more than 50 years old.22.1% of RE patients were accompanied with peptic ulcer. Only 4.0% of RE patients have typical reflux symptom. Patients with light mordent (Los Angeles System A , B ) RE were more than those with severe RE. Conclusion The detection rate of RE in our department is higher. RE is common in patients in presents. Most of RE are male and aged. Peptic ulcer might be the risk factor for RE. Endoscopy is very important for diagnosis of RE. 【Key word