有哪些信誉好的足球投注网站a green fluorescent protein with photoswitchable emission from the deep sea绿色荧光蛋白与photoswitchable从深海排放.pdfVIP
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a green fluorescent protein with photoswitchable emission from the deep sea绿色荧光蛋白与photoswitchable从深海排放
A Green Fluorescent Protein with Photoswitchable
Emission from the Deep Sea
1 1 2 1 3 4
Alexander Vogt , Cecilia D’Angelo , Franz Oswald , Andrea Denzel , Charles H. Mazel , Mikhail V. Matz ,
5 5,6 ¨ 1,7
Sergey Ivanchenko , G. Ulrich Nienhaus , Jorg Wiedenmann *
1 Institute of General Zoology and Endocrinology, University of Ulm, Ulm, Germany, 2 Department of Internal Medicine I, University of Ulm, Ulm, Germany, 3 NightSea,
Andover, Massachusetts, United States of America, 4 Integrative Biology, University of Texas in Austin, Austin, Texas, United States of America, 5 Institute of Biophysics,
University of Ulm, Ulm, Germany, 6 Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, 7 National Oceanography
Centre, University of Southampton, Southampton, United Kingdom
Abstract
A colorful variety of fluorescent proteins (FPs) from marine invertebrates are utilized as genetically encoded markers for live
cell imaging. The increased demand for advanced imaging techniques drives a continuous search for FPs with new and
improved properties. Many useful FPs have been isolated from species adapted to sun-flooded habitats such as tropical
coral reefs. It has yet remained unknown if species expressing green fluorescent protein (GFP)-like proteins also exist in the
darkness of the deep sea. Using a submarine-based and -operated fluorescence detection system in the Gulf of Mexico, we
discovered ceriantharians emitting bright green fluorescence in depths between 500 and 600 m and identified a GFP,
named cerFP505, with bright fluorescence emission peaking at 505 nm. S
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