a nationwide population-based cohort study will anxiety disorders increase subsequent cancer risk一个全国性的以人群为基础的队列研究焦虑症会增加后续的癌症风险.pdfVIP

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a nationwide population-based cohort study will anxiety disorders increase subsequent cancer risk一个全国性的以人群为基础的队列研究焦虑症会增加后续的癌症风险.pdf

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a nationwide population-based cohort study will anxiety disorders increase subsequent cancer risk一个全国性的以人群为基础的队列研究焦虑症会增加后续的癌症风险

A Nationwide Population-Based Cohort Study: Will Anxiety Disorders Increase Subsequent Cancer Risk? Ji-An Liang1,2., Li-Min Sun3., Kuan-Pin Su2,4, Shih-Ni Chang5,6,7,8, Fung-Chang Sung5,6, Chih- Hsin Muo5,6*, Chia-Hung Kao2,9* 1 Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan, 2 Institute of Clinical Medicine Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan, 3 Department of Radiation Oncology, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan, 4 Department of General Psychiatry Mind-Body Interface Laboratory, China Medical University Hospital, Taichung, Taiwan, 5 Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan, 6 Institute of Environmental Health, College of Public Health, China Medical University, Taichung, Taiwan, 7 The Ph.D. Program for Cancer Biology and Drug Discovery, China Medical University, Taichung, Taiwan, 8 Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, 9 Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan Abstract Background: The aim of this study was to evaluate a possible association between malignancy and anxiety disorders (AD) in Taiwan. Methods: We employed data from the National Health Insurance system of Taiwan. The AD cohort contained 24,066 patients with each patient randomly frequency matched according to age and sex with 4 individuals from the general population without AD. Cox’s proportional hazard regression analysis was conducted to estimate the influence of AD on the risk of cancer. Results: Among patients with AD, the overall risk of developing cancer was only 1% higher than among subjects without AD, and the difference was not significant (hazard ratio [HR] = 1.01, 95% confidence interval [95% CI] = 0.95–1.07). With regard to