a new approach to monitoring dengue activity一个新的监控方法登革热的活动.pdfVIP

Expert Commentary A New Approach to Monitoring Dengue Activity Lawrence C. Madoff1,2, David N. Fisman3,4,5*, Taha Kass-Hout6 1 Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, 2 Division of Epidemiology and Immunization, Massachusetts Department of Public Health, Boston, Massachusetts, United States of America, 3 Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada, 4 Departments of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, 5 Department of Medicine, University of Toronto, Toronto, Ontario, Canada, 6 Public Health Surveillance Program Office, Office of Surveillance, Epidemiology Laboratory Services, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America Among the world’s most vexing emerging infectious diseases, researchers. Event-based surveillance systems such as ProMED, dengue continues to spread, and in its many endemic areas is a GPHIN HealthMap and BioCaster rely on unofficial reports of major public health problem [1–3]. There is no vaccine available, disease, for example from clinicians or web-based healt-related and the immunology of dengue, whereby immunological ‘‘prim- news media, to report on disease outbreaks [15–17]. Such systems ing’’ can result in extremely severe manifestations (e.g., dengue have proven reliable and timely and informal sources of hemorrhagic fever) complicates vaccine development [4]. Thus information were even recognized in the 2005 revision of the dengue control is dependent on controlling the mosquito vector, International Health Regulations as important sources