a new view on lyme disease rodents hold the key to annual risk一个新的视图在莱姆病啮齿动物举行年度风险的关键.pdfVIP
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a new view on lyme disease rodents hold the key to annual risk一个新的视图在莱姆病啮齿动物举行年度风险的关键
Synopses of Research Articles
Inconspicuous Consumption: Uncovering the Molecular Pathways behind Phagocytosis
Mason Inman | DOI: 10.1371/journal.pbio.0040190
Eating at an Ethiopian restaurant The researchers found that
might give one an appreciation for the pseudopods extending around a
process of phagocytosis, a widespread particle activated ARF6 at their tips.
method immune cells use to ingest Then as the cell more fully enveloped
particles. To dine using injera, the a particle, ARF6 turned off, and
spongy Ethiopian fl atbread, you form activated ARF1 appeared throughout
a pocket of bread around the food that the pseudopod until it closed around
you pinch off and, with practice, stuff the particle. The discovery of a role for
cleanly into your mouth. Similarly, ARF1 was unexpected, since previous
when cells ingest small particles, studies suggested this protein is not
viruses, or other smaller cells by involved in phagocytosis. Also, the
phagocytosis, they extend protrusions researchers found that inhibiting PI-3K
called pseudopods around their target. prevented cells from switching be
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