a positive correlation between atypical memory b cells and plasmodium falciparum transmission intensity in cross-sectional studies in peru and mali之间的正相关典型记忆b细胞和恶性疟原虫传播强度在秘鲁和马里的横断面研究.pdfVIP

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a positive correlation between atypical memory b cells and plasmodium falciparum transmission intensity in cross-sectional studies in peru and mali之间的正相关典型记忆b细胞和恶性疟原虫传播强度在秘鲁和马里的横断面研究.pdf

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a positive correlation between atypical memory b cells and plasmodium falciparum transmission intensity in cross-sectional studies in peru and mali之间的正相关典型记忆b细胞和恶性疟原虫传播强度在秘鲁和马里的横断面研究

A Positive Correlation between Atypical Memory B Cells and Plasmodium falciparum Transmission Intensity in Cross-Sectional Studies in Peru and Mali 1 2,3 1 4 4 4 Greta E. Weiss , Eva H. Clark , Shanping Li , Boubacar Traore , Kassoum Kayentao , Aissata Ongoiba , 3 4 1 2,3,5 1 Jean N. Hernandez , Ogobara K. Doumbo , Susan K. Pierce , OraLee H. Branch , Peter D. Crompton * 1 Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America, ´ 2 Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 3 Laboratorio de Investigacion de Productos Naturales Antiparasitarios de la Amazonia (LIPNAA), Universidad Nacional de la Amazonia Peruana, Iquitos, Loreto, Peru, 4 Malaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy, and Odonto-Stomatology, University of Bamako, Bamako, Mali, 5 Department of Medical Parasitology, New York University, New York, New York, United States of America Abstract Background: Antibodies that protect against Plasmodium falciparum (Pf) malaria are only acquired after years of repeated infections. The B cell biology that underlies this observation is poorly understood. We previously reported that ‘‘atypical’’