a research agenda for malaria eradication vector control根除疟疾病媒控制的研究议程.pdfVIP

Review A Research Agenda for Malaria Eradication: Vector Control The malERA Consultative Group on Vector Control * To develop vector-targeted interventions in support of malaria Abstract: Different challenges are presented by the eradication in all disease endemic settings that are unfettered by variety of malaria transmission environments present in these limitations, three challenges need to be recognized and the world today. In each setting, improved control for addressed with great urgency today. The first challenge, for which reduction of morbidity is a necessary first step towards near-term product development is essential, is the preservation the long-range goal of malaria eradication and a priority and improvement of the utility of existing insecticide-based for regions where the disease burden is high. For many geographic areas where transmission rates are low to interventions. This challenge will require a vibrant research moderate, sustained and well-managed application of agenda that develops a broader range of insecticides with novel currently available tools may be sufficient to achieve local modes of action that can circumvent emerging resistance to elimination. The research needs for these areas will be to existing insecticides, particularly the pyrethroids. This agenda sustain and perhaps improve the effectiven