a systematic review on renal and bladder dysfunction after endoscopic treatment of infravesical obstruction in boys系统回顾在内镜治疗后肾和膀胱功能障碍infravesical阻塞的男孩.pdfVIP
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a systematic review on renal and bladder dysfunction after endoscopic treatment of infravesical obstruction in boys系统回顾在内镜治疗后肾和膀胱功能障碍infravesical阻塞的男孩
A Systematic Review on Renal and Bladder Dysfunction
after Endoscopic Treatment of Infravesical Obstruction in
Boys
1 2 1 1,3
Pauline M. L. Hennus *, Geert J. M. G. van der Heijden , J. L. H. Ruud Bosch , Tom P. V. M. de Jong ,
Laetitia M. O. de Kort1
1 Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands, 2 Department of Epidemiology, Division Julius Center for Health Sciences and
Primary Care, and Department Otorhinolaryngology, Division Surgical Specialties, University Medical Center Utrecht, Utrecht, The Netherlands, 3 Pediatric Renal Center
Wilhelmina Children’s Hospital and University Medical Center Utrecht and Elisabeth Children’s Hospital and Academic Medical Center Amsterdam, Amsterdam, The
Netherlands
Abstract
Background: Posterior urethral valves (PUV) may cause subtle to severe obstruction of the urethra, resulting in a broad
clinical spectrum. PUV are the most common cause of chronic renal disease in boys. Our purpose was to report the
incidences of kidney and bladder dysfunction in boys treated with endoscopic valve resection for PUV.
Methodology: We searched MEDLINE and EMBASE databases until 1st of July 2011, to identify original papers that
described outcome of endoscopic valve resection (EVR) in boys. We extracted information on (1) patient characteristics and
clinical presentation of PUV related to outcomes and (2) the post-treatment absolute risks for kidney and bladder
dysfunction.
Principal findings: Thirty-four studies describing renal function, vesicoureteral reflux (VUR), incontinence, and urodynamic
bladder function after E
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