a systematic review of the frequency of neurocyticercosis with a focus on people with epilepsy频率的系统回顾neurocyticercosis关注癫痫患者.pdfVIP
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a systematic review of the frequency of neurocyticercosis with a focus on people with epilepsy频率的系统回顾neurocyticercosis关注癫痫患者
A Systematic Review of the Frequency of
Neurocyticercosis with a Focus on People with Epilepsy
1 ´ ` 1 2 1 3
Patrick C. Ndimubanzi , Helene Carabin *, Christine M. Budke , Hai Nguyen , Ying-Jun Qian , Elizabeth
1 1 1 1
Rainwater , Mary Dickey , Stephanie Reynolds , Julie A. Stoner
1 Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, 2 Department of
Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas AM University, College Station, Texas, United States of America, 3 National Institute of Parasitic
Diseases, Shangai, People’s Republic of China
Abstract
Background: The objective of this study is to conduct a systematic review of studies reporting the frequency of
neurocysticercosis (NCC) worldwide.
Methods/Principal Findings: PubMed, Commonwealth Agricultural Bureau (CAB) abstracts and 23 international databases
were systematically searched for articles published from January 1, 1990 to June 1, 2008. Articles were evaluated for
inclusion by at least two researchers focusing on study design and methods. Data were extracted independently using
standardized forms. A random-effects binomial model was used to estimate the proportion of NCC among people with
epilepsy (PWE). Overall, 565 articles were retrieved and 290 (51%) selected for further analysis. After a second analytic phase,
only 4.5% of articles, all of which used neuroimaging for the diagnosis of NCC, were reviewed. Only two studies, both from
the US, estimated an incidence rate of NCC using hospital discharge data
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