- 1、本文档共33页,可阅读全部内容。
- 2、有哪些信誉好的足球投注网站(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
The renaissance of immunotherapy is a (免疫疗法是一个文艺复兴时期)
The renaissance of immunotherapy is a revolution
for cancer patients and for oncology
Ira Mellman, Ph.D.
Vice President, Cancer Immunology, Genentech
1
The renaissance of immunotherapy is a revolution
for cancer patients
Traditional drug development
Is linear development path the best approach?
Generate Test Verify
Launch
Hypothesis Hypothesis Hypothesis
Early Late
Research Marketing
Development Development
Cancer immunotherapy requires a cyclical
“learning organization”
Post-Launch Research
Cancer Immunotherapy
Strategy Group
(CITS)
Late Development Early Development
FIR PII 1/2L Dx+ ORR
BIRCH
PII Dx+ ORR
POPLAR PII 2L+ Dx+/- vs. Doce OS
OAK PIII 2L+ Dx+/- vs. Doce OS
Cancer immunotherapy at Genentech/Roche
Pipeline overview
Pre-clinical Phase I Phase II Phase III
Anti-PDL1 Anti-PDL1 Anti-PDL1
ImmTAC
Solid tumors NSCLC (Dx+) NSCLC 2/3 L
Ant
您可能关注的文档
- The Optimal Scope of the Royalty Base in Patent (最优专利版税基地的范围).pdf
- The Orbit Valve(轨道阀).pdf
- The Order Fulfillment Process Model YAWL(订单履行流程模型小帆船).pdf
- THE ORE MICROSCOPE Mineralogical Society (矿石显微镜矿物学的社会).pdf
- The Origin of Modern Astronomy University of (大学现代天文学的起源).pdf
- THE ORIGINS OF SACRED GEOMETRY Ning(神圣几何学Ning的起源).pdf
- The Orlando Materials Innovation Welcome to (欢迎来到奥兰多材料创新).pdf
- The Outdoor recreation economy(户外休闲经济).pdf
- The Outlook for Automotive Transmission …(汽车变速器的前景u2026).pdf
- THE ORIGINS OF THE QUANTUM THEORY W(量子理论的起源).pdf
文档评论(0)