D二聚体定量测定对妊娠期高血压疾病产后出血的预测价值.docVIP

D-二聚体定量测定对妊娠期高血压疾病产后出血的预测价值 摘要目的探讨D-二聚体定量测定对妊娠期高血压疾病患者产后出血的预测价值。方法 选取我院2013年1月至2014年2月收治的150例妊娠期高血压患者进行D-二聚体定量检测分析，单因素方差分析分娩前24小时内D-二聚体测量值与分娩后24小时内失血量的相关性，以ROC曲线分析其对妊娠期高血压疾病患者产后出血的预测截断值。 结果 150例患者分娩前24小时内D-二聚体水平显著升高，并发产后出血28例，率18.7%（28/150）。妊娠期高血压疾病并发产后出血比分娩前24小时内D-二聚体水平显著升高（P＜0.01）。ROC曲线下方积为O.848，其标准误差为0.042，95％可信区域为0.766—0.930。最佳临界值为2.26mg/L，此时特异度为66.4%，灵敏度为92.9%，youden指数0.593。结论 D-二聚体定量测定对妊娠期高血压疾病产后出血预测有较高价值，以2.26mg/L作为预测截断值最合适。 Predictive Value of Quantitative Determination of D-dimer on Postpartum Hemorrhage from Hypertensive Disorder in Pregnancy Abstract Objective To explore the predictive value of quantitative determination of D-dimer on postpartum hemorrhage from patients with hypertensive disorders in pregnancy. Methods :150 cases of pregnancy-induced hypertension patients who were treated in our hospital from January 2013 to February 2014 were randomly divided into two groups, give them D-dimer detection analysis, and do the single factor analysis of variance between 24 hours before delivery and the two D- dimer measurements and blood loss within 24 hours after delivery quantity .Finally, analyze the prediction of truncated postpartum hemorrhage in patients with hypertension syndrome of pregnancy and its value using ROC curve. Results the two D- dimer levels of the 150 patients 24 hours before delivery were significantly increased.Among them, 28 cases generated postpartum hemorrhage, and the incidence was 18.67% (28/150);The treatment group was better than the control in the aspect of 24 hours before delivery D-dimer levels,there was statistical significance(P0.01) between the two groups.Area under the ROC curve was O.848, and its standard error is 0.042,95% CI 0.766-0.930 region. Best critical value of 2.26mg / L, this time a specificity of 66.4%, a sensitivity of 92.9%, youden index of 0.593. Conclusion Quantitative determination of D-dimer on hypertensive disorders in pregnancy has high value in predicting postpartum hemorrhage, and the most appro