冻干技术及其在中药冻干制剂中应用的研究进展.pdf

冻干技术 及其在中药冻干制剂中 应用的研究进展 △刘嘉刘汉清 南京中医药大学南京210046 【摘要】本文在阐述冻干技术原理、特点的基础上，分析评价了冻干各阶段的影响因素， 介绍了中药冻干制剂的冻干损伤和保护剂研究概要，明确了中药冻干制剂质量评 价的基本指标，并就中药冻干制剂配液等相关工艺进行了探究，对冻干技术在中 药冻干制剂研究中的应用具有重要参考价值。 【关键词】真空冷冻干燥；冻干技术原理： 冻干各阶段的影响因素；中药冻干制剂；冻干保 护剂；冻干制剂配液工艺 TheVacuum Freeze—desiccation and theResearch 11echnology ofIts in Progressions Chinesefreeze Application DryingDrugs Preparation ’Liu JiaLiu Hanqlng ofChinese NanjlngUn；Versity TraditionalMedicine210046 NanjIng 【Abstract】ontherOundofthe g introductionOfthe and principIefeatures0fVacuum rreeze—des』ccatfon evaiuates technofOgy，thfspaper each Offfeeze—d stage rV and its technolOgy factOr，intrOductstraditional influencing Chinesefreeze—drv preparatlon。s and treeze—dyIngdamageprOtectiVeadditive，identifi