海洋药物化学知识点（Marine medicine chemistry knowledge point）.docVIP

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海洋药物化学知识点（Marine medicine chemistry knowledge point）.doc

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海洋药物化学知识点（Marine medicine chemistry knowledge point）

海洋药物化学知识点（Marine medicine chemistry knowledge point） Knowledge points of marine medicine review - Ocean class 091, WHY Examination emphasis Fill in the blanks 1, have medicinal value of algae: Cyanophyta, Chlorophyta, Rhodophyta, phaeophyta. 2, the two phases of drug discovery: drug discovery and drug discovery New varieties: marine organisms, traditional Chinese medicine and natural drugs; marine biological chemicals; marine biological products 3, Chinas drug safety evaluation standard: Chinese herbal medicine production quality management standards (good, agriculture, practice, GAP) manufacturingpractices (good manufacture, practice, GMP), GLP (good, laboratory, practice, GLP), drug clinical trials, quality management practices (good, clinical, practice, GCP), drug supply quality management practices (good, supply, practice, GSP) The characteristics of 4 mangrove plants (1) has the characteristics of viviparous (2) root strange (3) rich in tannins (4) leaves with high osmotic pressure, tube structure of secondary xylem in small diameter, high density distribution: to absorb water from the sea. 5. The preparation methods of oligosaccharides are acid hydrolysis, enzyme hydrolysis, oxidation degradation and microwave degradation 6, the special nature of the marine organisms growing environment Characteristics of marine environment: low temperature, less oxygen, lack of light, high salinity and high pressure; High salt, high pressure, low temperature and light of the closed system, resulting in marine organisms has significant characteristics in survival mode, and a series of The new supersedes the old. adaptation mechanism and many other aspects, embodies the special structure contains many bio active substances and metabolites in the body. 7. What kinds of drug design do you include? Based on the design of small molecule drugs (Ligand-based drug design, LBDD): according to the structure of existing drugs, physicochemical properties and activity relationship (SAR) an