循证实践指引的制定国际经验与中国实践-兰州大学.pdf

第42 卷 第1期 兰州大学学报（医学版） Vol.42 No. 1 2016 年2 月 Journal of Lanzhou University （Medical Sciences ） Feb. 2016 文章编号：1000-2812 (2016) 01-0029-07 循证实践指南的制定：国际经验与中国实践 1,2,3 1,2,3 1,2,3 4 陈耀龙 ，杨克虎 ，田金徽 ，Amir Qaseem 1. 兰州大学基础医学院 循证医学中心，甘肃 兰州 730000 2. 兰州大学 甘肃省循证医学与临床转化重点实验室，甘肃 兰州 730000 3. 兰州大学 中国GRADE 中心，甘肃 兰州 730000 4. 美国医生协会，美国 费城 19106 摘要：随着指南定义的更新及方法学的发展，国内外发布的指南数量不断增多，但其质量良莠不齐，各个国际指南组 织也针对这一问题制定了高质量循证指南的原则和标准，同时出版指南制定手册阐述严谨透明的步骤和方法。本文基 于国内外经验，总结了中国指南制定面临的机遇和挑战，并提出改进建议：政府、协会/学会层面倡导循证实践指南的 制定；加强指南的研究与合作；注重指南的注册与评审。 关键词：临床实践指南；循证医学；指南制定 中图分类号：R-03 文献标识码：A doi ：10.13885/j.issn. 1000-2812.2016.01.006 Development of evidence-based practice guidelines: international experience and Chinese practice Chen Yao-long1,2,3 ，Yang Ke-hu1,2,3 ，Tian Jin-hui1,2,3 ，Amir Qaseem4 1. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China 2. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, Lanzhou 730000, China 3. Chinese GRADE Center, Lanzhou University, Lanzhou 730000, China 4. American College of Physicians, Philadelphia 19106, USA Abstract ：：With the update of definition of practice guideline and the development of guideline methodology, more and more practice guidelines were published in China and abroad ，however, the guidelines is of varying quality. To improve the practice guidelines, many international guideline organizations developed the criteria and standards for high-quality evidence-based practice guidelines, and published guideline development hand- books describing rigorous and transparent steps and methods. Based on the experience of developing guide- lines from China and abroad, this article summarized the opportunities and challenges of the guidelin