三维电子线放射治疗剂量计算方法的研究及实现.doc

三维电子线放射治疗剂量计算方法的研究与实现 翁邓胡 徐海荣 南方医科大学生物医学工程学院，广东 广州 510515 摘要：目的：研究和实现了一种基于CT图像的三维电子线放射治疗计算方法。方法：采集临床鼻腔筛窦肿瘤患者的CT图像，通过Visual C++开发工具对CT图像进行DICOM解析，获取相关的数据，建立仿真人体矩阵信息，用以剂量模型的计算，包括斜入射校正和组织不均匀性校正。采用VTK技术重建出CT图像的矢状面和冠状面，根据剂量模型计算的剂量值，生成横断面、矢状面以及冠状面的等剂量分布曲线。结果：根据面向对象的分析和设计理念，开发了交互式界面易操作，可视化程度高的治疗计划软件；给定靶区剂量计算得到加速器输出剂量；高剂量线能很好的适形靶区，并使正常组织和关键器官所受剂量很小，而得到保护。结论：实现电子线放射治疗患者体内剂量的可视化，直观显示剂量分布，对提高患者的放射治疗质量和精确放疗的后续研究具有指导意义。 关键词：电子线放射治疗；剂量计算；等剂量分布 Research and implementation of a 3d dose calculation method for electron beam irradiation WENG Deng-hu , XU Hai-rong School of Biomedical Engineering, Southern Medical University, Guangzhou 510515 Abstract:Objective:To study and implement a 3d electron beam dose calculation method based on CT images.Methods:This paper collected CT images with patients for carcinomas of the nasal cavity and the ethmoid sinus.Microsoft Visual C++ was used to parse CT images for related infor- mation,then to build the human body emulatimal matrix for the dose model calculation including oblique incidence correction and tissue inhomogeneity correction.We reconstructed the sagittal and coronal images in the 3D display using VTK technique.The dose distribution displayed on CT images was processed by the dose distribution calculation methods.Results:According to the object-oriented analysis and design concept,we developed the interactive interface, easy operation visualized treatment planning software.Besides,it can calculate accelerator output dose(MU) by given target area dose.High doses line can be a very good conformal target area, and normal tissue and key organ by dose is small, and protected.Conclusion:This planning software we developed has realized the dose visualization with patients in electron beam radiation therapy,and visually displayed dose distribution,it has the guiding significance to further improve the radiation treatme- nt quality with patients and accurate radiotherapy of subsequent research. Key words:electron beam irradiation;dose calcul