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Bioresorbable DES Update
CCVVC 2015
Mathew Samuel, MD, DM
Apollo Hospitals, Chennai,
Lilavati Hospital,
Mumbai, India
CONFLICT OF INTEREST:
I, Dr Samuel Mathew DO NOT have a
financial interest/arrangement or
affiliation with one or more
organizations that could be perceived
as a real or a arent conflict of
interest in the context of the subject
of this presentation.
First: Why Do We Need BVS?
Stents vs. Balloon Angioplasty for STEMI:
Very-Late Events Greater for Metallic Stents ( 1 yr)
Stent or Lesion Thrombosis Target Vessel Reinfarction
Brodie et al, J Interven Cardiol 2014:27: 21-28
BEST Trial: MV XV DES v CABG
After 1 year, TLF occurs at a rate of
2.2% per year, year after year, with
no flattening of the slope
The Future in PCI is to Move Away from Permanent
Implants to
Fully Resorbable Devices
®
1 2
Caution: Investigational device.
Limited by Federal U.S. law
to investigational use only.
1. in vitro drug elution model.
2. J. Lane, et. al., Long Term Vascular Safety of an Everolimus-eluting BVS With Benign Positive Remodeling and Late Luminal Gain in Porcine Coronary Arteries as Assessed by OCT , IVUS, and
Histology. Poster, PCR 2013.
Note: Histology im
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