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中药胶剂修复半月板损伤的试验研究-中国骨伤
∀ 456 ∀ 2000 8 13 8 China J Orthop T rauma, August 2000, Vol. 13, No. 8
张磊 高云 吴林生
( , 100700)
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Meniscal repair using a Chinese herbal medicinal gel: an experimental study in rabbits ZHA N G Lei, GA O
Yun, W U Linsheng. I ns titute of Orthop edics and Traumatolog , China A cadem of TCM ( Beij ing,
100700)
Abstract Objective To study t he effect of a Chinese her al gel on repair of meniscal injury, in order
to find an easy and effect ive w ay to promote the repair of this injury, especially those in the avascular portion.
Methods Eight healthy adult white ra its w ith ig ears, 3kg w eight or so w ithout limitation in sex were fed
in the same condit ions. The animals were randomly divided into two groups: t he control and gelat in control
groups. In gelatin group, Chinese her al medicinal gel was implanted into one side of meniscal lesion while no
management w as done in t he contralateral side of the uninjuried meniscus. In gelatin control group, Chinese
her al medicinal gel w as implanted into one side of lesion and gelatin ( Sigma. Co. TAPE B) w hose physical
properties w ere similar w ith the Chinese medicinal gel w as implanted into ot her side.T he gelatin control w as
esta lished so as to prove t he repairing effect of the Chinese her al gel depending not only on it! s physical ac
tion, ut to a larger extent on it! s pharmacological action.T he meniscus w ere cut transversely at the anterior
1/ 3 of medial meniscus. Models in oth sides w ere esta lished and Chinese her al medicinal gel w as implanted
into one side of lesion.T he other side served as the control group. The animals w ere sacrificed at 6t h, 12t h and
24t h weeks respectively after operat ion. T he specimens were removed for gross o servat ion, histological and
scanning microscope o servations and iomechanical testing
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