2型糖尿病合并腰椎骨质疏松的临床相关因素分析.pdfVIP

·1546。doi JSouthMed 10．3969／j．issn2016．11．17 临床研究 2型糖尿病合并腰椎骨质疏松的I觫相关因素分析 张玉娴，闵少雄 南方医科大学珠江医院骨科一区，广东广州510280 摘要：目的分析2型糖尿病骨质疏松患者腰椎骨密度(BMD)与年龄、性别、体质量、病程、空腹血糖等因素的相关性。方法收 集临床资料完整的2型糖尿病合并骨质疏松患者40例为A组，使用倾向得分匹配法(PsM)确定年龄性别匹配的同期健康体检 者40例为B组，两组病例均测定腰椎(L．～L4)及左侧股骨BMD，并记录性别、年龄、病程、体质量指数、空腹血糖及血钙、血磷、尿 关，并与病程呈负相关，而与体质量指数(BMI)、空腹血糖、尿钙、尿磷呈正相关，但与年龄、血钙、血磷无明显相关关系。结论2 型糖尿病患者骨密度降低与性别、BMI、病程延长、血糖控制不佳等因素有关。 关键词：2型糖尿病；骨质疏松；骨密度 ofclinicalfactors 2 with in with diabetes type Analysis correlatingosteoporosispatients mellitus ZHANG Yuxian,MIN Shaoxiong Medical 510280，China Department Hospital,Southern ofOrthopedics，Zhujiang University,Guangzhou To theclinicalfactorsthatcontributetoloweredbonemineral thelumbar Abstract：0bieetiveanalyze density∞MD)of in vertebrae 2diabetic 2diabetic with and40 type patients．MethodsFortytype patientsosteoporosisage-and score examinedforBMDoftheL1toL4 individuals,selected method,were gender-matchedhealthy usingpropensity vertebraeandtheleft ofthe mass blood caldum, femur．Age,gender,coursedisease,bodyindex(BMD，fastingglucose,serum seruIn caldum,and were betweenthetwo BMDoftheL1to urinary groups．Results phosphate,urinary phosphatecompared L4vertebraswas lowerinthediabeticthaninthe individuals thediabetic significantly group healthy fP0．05)．In patient,