重复经颅磁刺激对创伤后应激障碍患者创伤心理的-第三军医大学学报.docVIP

rTMS对创伤后康复期PTSD患者核心症状、正负性情绪 和心理弹性的影响 王 艺1，2 ，彭 李2，周贤丽1，刘宏亮1，李 敏2（400038重庆，第三军医大学：西南医院康复科1，心理学院军事心理学教研室2） 【摘要】：目的：研究高频重复经颅磁刺激（rTMS）对创伤后应激障碍（PTSD）患者核心症状、正负性情绪和心理弹性的影响。方法：将40例伴有创伤后应激障碍症状（PTSD评分38分20例，接受20Hz高频rTMS右侧前额叶背外侧区域（DLPFC)0例，采用假性rTMS，刺激部位同治疗组比较组患者治疗前后、心理弹性和正负性情绪水平的变化P0.01），但心理弹性得分前后差异没有统计学显著性(P0．05)。对照组假刺激前后在各项评分上均没有明显差异(P0．05)。结论：20Hz高频重复经颅磁刺激可提高患者的积极情绪，减少负性情绪，有效缓解创伤后应激障碍核心症状，作为一种干预创伤心理的有效手段，值得推广。 【关键词】：重复经颅磁刺激；创伤后应激障碍；负性情绪；正性情绪；心理弹性 Effect of Repetitive Transcranial Magnetic Stimulation to core symptoms、Positive and Negative Affectresilience in rehabilitation patients with Posttraumatic Stress Disorder after traumatic injury Wang Yi1,2, ,Peng Li2, Zhou Xian Li1 , Liu Hong Liang1, Li Min2(1 Department of Rehabilitation，Southwest Hospital, 2 Department of Military Psychology,Academy of Psychology,Third Military Medical University,ChongQing,400038，China) ［Abstract］ Objective: The efficacy of Repetitive Transcranial Magnetic Stimulation(rTMS) to core symptoms、ositive and negative affect、resilience was studied in rehabilitation patients with Posttraumatic Stress Disorder(PTSD) after traumatic injury. Methods: patients （PTSD score38）with dysfunction after traumatic injury were assigned to the following groups：Active group(20 subjects) receive 20Hz rTMS to the right dorsolateral prefrontal cortex(DLPFC); Control group(0 subjects) receive sham rTMS to the same area. Treatments were administered in 10 daily sessions over 2 weeks. Two groups were assessed at before and after 10 rTMS sessions according to the PTSD Checklist-Civilian Version(PCL-C), Connor-Davidson Resilience Scale(CD-RISC) and Positive and Negative Affect Scale(PANAS). Compare the two groups in PTSD, resilience, positive and negative emotional level changes before and after treatment. Results:The 10 daily treatments of 20Hz rTMS to right DLPFC induced a significant improvements in PTSD core symptoms、positive and negative affect（P0.01）, but resilience had not markedly improved with this treatment(P0．05)